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    Nardosinonediol
    Information
    CAS No. 20489-11-6 Price
    Catalog No.CFN89546Purity>=98%
    Molecular Weight252.34Type of CompoundSesquiterpenoids
    FormulaC15H24O3Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Nardosinonediol Description
    Source: The herbs of Nardostachys jatamansi
    Biological Activity or Inhibitors: 1. Nardosinonediol shows cytotoxic activity against P-388 cells.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.9629 mL 19.8145 mL 39.6291 mL 79.2581 mL 99.0727 mL
    5 mM 0.7926 mL 3.9629 mL 7.9258 mL 15.8516 mL 19.8145 mL
    10 mM 0.3963 mL 1.9815 mL 3.9629 mL 7.9258 mL 9.9073 mL
    50 mM 0.0793 mL 0.3963 mL 0.7926 mL 1.5852 mL 1.9815 mL
    100 mM 0.0396 mL 0.1981 mL 0.3963 mL 0.7926 mL 0.9907 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Nardosinonediol References Information
    Citation [1]

    Chem Pharm Bull (Tokyo). 1993 Jun;41(6):1183-4.

    Cytotoxic sesquiterpenes from Nardostachys chinensis.[Pubmed: 8370115]
    Five cytostatic sesquiterpenes, desoxo-narchinol-A (1), nardosinone (2), debilon (3), Nardosinonediol (4) and kanshone A (5), were isolated from the roots and rhizomes of Nardostachys chinensis (Valerianaceae). The steric structure of 1 was determined by nuclear Overhauser effects (NOEs) and the exciton chirality method. All five showed cytotoxic activity against P-388 cells and the structure-activity relationship of 1 was also discussed.