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Neocaesalpin O
Neocaesalpin O
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Neocaesalpin O
Price:
CAS No.: 1053189-53-9
Catalog No.: CFN96963
Molecular Formula: C26H34O10
Molecular Weight: 506.54 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Caesalpinia minax HANCE.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Description: Neocaesalpin O is a natural product from Caesalpinia minax HANCE.
In vitro:
Chem Pharm Bull (Tokyo). 2012;60(6):759-63.
The new cassane-type diterpenes from Caesalpinia minax.[Pubmed: 22689428]

METHODS AND RESULTS:
Four new cassane-type diterpenes, Neocaesalpin S (1), Neocaesalpin T (2), Neocaesalpin U (3), and Neocaesalpin V (4) were isolated from Caesalpinia minax HANCE together with seven known compounds Neocaesalpin A (5), Neocaesalpin K (6), Neocaesalpin L (7), Neocaesalpin M (8), Neocaesalpin O (9), Neocaesalpin MP (10), and Magnicaesalpin (11). Their structures were elucidated on the basis of 1D- and 2D-NMR, MS, and circular dichroism (CD) analysis.
CONCLUSIONS:
Compounds 1-4 were tested against liver cancer (HepG-2) and breast cancer (MCF-7), and showed mild antiproliferative activity.
Neocaesalpin O Description
Source: The herbs of Caesalpinia minax HANCE.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

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ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9742 mL 9.8709 mL 19.7418 mL 39.4836 mL 49.3544 mL
5 mM 0.3948 mL 1.9742 mL 3.9484 mL 7.8967 mL 9.8709 mL
10 mM 0.1974 mL 0.9871 mL 1.9742 mL 3.9484 mL 4.9354 mL
50 mM 0.0395 mL 0.1974 mL 0.3948 mL 0.7897 mL 0.9871 mL
100 mM 0.0197 mL 0.0987 mL 0.1974 mL 0.3948 mL 0.4935 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN892757-O-Acetylbonducellpin C197781-86-5462.53C25H34O8
CFN9695114-Deoxy-epsilon-caesalpin279683-46-4418.53C24H34O6
CFN96258Isovouacapenol C455255-15-9438.6C27H34O5
CFN91966Ajuforrestin A157110-18-4324.37C20H20O4
CFN96963Neocaesalpin O1053189-53-9506.54C26H34O10
CFN89372Neocaesalpin L952473-86-8524.55C26H36O11
CFN9631912-Demethylneocaesalpin F1228964-10-0470.6C27H34O7
CFN890317-O-Acetylneocaesalpin N1309079-08-0494.53C25H34O10
CFN89378Minaxin C1418150-06-7542.57C26H38O12
CFN89082Caesalpine A1616757-59-5420.50C23H32O7
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