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    Nephthenol
    Nephthenol
    Information
    CAS No. 53915-41-6 Price
    Catalog No.CFN91050Purity>=98%
    Molecular Weight290.49Type of CompoundDiterpenoids
    FormulaC20H34OPhysical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison
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    Our products had been exported to the following research institutions and universities, And still growing.
  • Korea Food Research Institute(KF... (Korea)
  • Worcester Polytechnic Institute (USA)
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  • Colorado State University (USA)
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  • Package
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    Biological Activity
    Description: 1. Nephthenol shows antiproliferative activity against the cell lines HUVEC and K-562 and for cytotoxicity against the cell line HeLa.
    Nephthenol Description
    Source: The herbs of Boswellia carterii Birdw.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi: 10.1016/j.phymed.2017.12.030.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.4425 mL 17.2123 mL 34.4246 mL 68.8492 mL 86.0615 mL
    5 mM 0.6885 mL 3.4425 mL 6.8849 mL 13.7698 mL 17.2123 mL
    10 mM 0.3442 mL 1.7212 mL 3.4425 mL 6.8849 mL 8.6061 mL
    50 mM 0.0688 mL 0.3442 mL 0.6885 mL 1.377 mL 1.7212 mL
    100 mM 0.0344 mL 0.1721 mL 0.3442 mL 0.6885 mL 0.8606 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Nephthenol References Information
    Citation [1]

    Chem Biodivers. 2010 Aug;7(8):2007-15.

    Terpenes from the soft corals Litophyton arboreum and Sarcophyton ehrenbergi.[Pubmed: 20730963 ]
    The new cembrane diterpene (3E,11E)-cembra-3,8(19),11,15-tetraene-7alpha-ol (1), Nephthenol (2), and all-trans-peridinin (3) have been isolated from the soft coral Litophyton arboreum. The tetraterpene 3, (+)-7,8-epoxy-7,8-dihydrocembrene C (4), emblide (5), sarcophytoxide (6), sarcoglaucol-16-one (7), guajacophine (8), and 1,4-peroxymuurol-5-ene (9) have been obtained from the soft coral Sarcophyton ehrenbergi. The compounds were characterized primarily by NMR spectroscopy. Some of the terpenes were tested for their antiproliferative activity against the cell lines HUVEC and K-562 and for cytotoxicity against the cell line HeLa, and they showed moderate activities.
    Citation [2]

    Nat Prod Res. 2018 May 17:1-7.

    New cembrane-type diterpenoids from Bornean soft coral Nephthea sp. with antifungal activity against Lagenidium thermophilum.[Pubmed: 29772929 ]
    Three new cembrane diterpenes, nephthecrassocolides A-B (1-2) and 6-acetoxy Nephthenol acetate (3) along with three known compounds, 6-acetoxy-7,8-epoxy Nephthenol acetate (4), epoxy Nephthenol acetate (5) and Nephthenol (6) were isolated from one population of Nephthea sp. Their structures were elucidated based on spectroscopic data analysis and the antifungal activities of compounds 1-6 were evaluated.