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Olivetol
Olivetol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Olivetol
Price: $30 / 20mg
CAS No.: 500-66-3
Catalog No.: CFN97735
Molecular Formula: C11H16O2
Molecular Weight: 180.24 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The leaves of Grevillea robusta.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $7.0 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Olivetol is a precursor in various syntheses of tetrahydrocannabinol. It acts as a competitive inhibitor of the cannabinoid receptors CB1 and CB2. Olivetol has antioxidant effects.
In vitro:
Se Pu. 2013 Jun;31(6):587-95.
Preparation and evaluation of molecularly imprinted polymer of olivetol for solid phase extraction.[Pubmed: 24063201]
Molecularly imprinted polymer (MIP) was synthesized by bulk polymerization, using Olivetol as template molecule, methyl acrylic acid (MAA) as monomer, ethylene glycol dimethacrylate (EDMA) as crosslinker, toluene and dodecanol as solvents.
METHODS AND RESULTS:
The resulted MIP was characterized by the equilibrium binding experiments, scanning electron microscope (SEM) and Fourier transform infrared spectrometer (FTIR). The polymer was then applied to solid phase extraction (SPE) of Olivetol from spiked wheat bran samples. From the equilibrium binding experiments, it was showed that MIP had a better recognizability for the template molecule. Scatchard analysis showed that MIP had specific adsorption to Olivetol with two classes of binding sites. The high and low binding sites dissociation constants were 0.021 and 1.002 mmol/L. The corresponding maximum binding capacities were 18.74 and 135.9 micromol/g, respectively. Under the optimum condition of SPE, the recoveries of Olivetol on MIP cartridge were in the range of 97.8% - 98.8%. The relative standard deviations (RSDs) were 2.8% -4.2%. The linearity range was between 0.1 and 100 mg/L. The limit of detection (S/N = 3) was 0.062 mg/L.
CONCLUSIONS:
MIP cartridge showed stronger selectivity, higher recovery and purified the sample more drastically compared with non-imprinted polymer (NIP) cartridge and commercial poly (styrene/divinyl-benzene) (PLS) cartridge.
Free Radic Res. 1998 Apr;28(4):359-68.
Quantum mechanical and experimental oxidation studies of pentadecylresorcinol, olivetol, orcinol and resorcinol.[Pubmed: 9684980]
Resorcinols (pentadecylresorcinol, Olivetol, orcinol and resorcinol) exhibit antioxidant properties in liposomal systems. Antioxidant potency depends on the length of the alkyl chain.
Olivetol Description
Source: The leaves of Grevillea robusta.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.5482 mL 27.7408 mL 55.4816 mL 110.9632 mL 138.704 mL
5 mM 1.1096 mL 5.5482 mL 11.0963 mL 22.1926 mL 27.7408 mL
10 mM 0.5548 mL 2.7741 mL 5.5482 mL 11.0963 mL 13.8704 mL
50 mM 0.111 mL 0.5548 mL 1.1096 mL 2.2193 mL 2.7741 mL
100 mM 0.0555 mL 0.2774 mL 0.5548 mL 1.1096 mL 1.387 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Nat Prod. 1984 Sep-Oct;47(5):828-34.
Biotransformation of olivetol by Syncephalastrum racemosum.[Pubmed: 6512535]

METHODS AND RESULTS:
A study of the biotransformation of Olivetol by Syncephalastrum racemosum ATCC 18192 has led to the isolation of three metabolites, which were identified as 4'-hydroxy-Olivetol, 3-(3,5-dihydroxyphenyl)-1-propanol, and 3-(3,5-dihydroxyphenyl)-1-propanoic acid. The structures of the isolated metabolites were deduced by comparison of their spectral properties (pmr, cmr, ms) with those of Olivetol. The absolute configuration of 4'-hydroxy-Olivetol was determined to be R by the Horeau partial resolution method.
CONCLUSIONS:
Biotransformation of Olivetol therefore appears to occur by a subterminal oxidation process.
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