Otophylloside F | CAS:250217-73-3 | Manufacturer ChemFaces

Otophylloside F

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Otophylloside F Description

Source:	The roots of Cynanchum otophyllum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

J Nat Prod. 2015 Jul 24;78(7):1548-55.

Bioactive C21 Steroidal Glycosides from the Roots of Cynanchum otophyllum That Suppress the Seizure-like Locomotor Activity of Zebrafish Caused by Pentylenetetrazole.[Pubmed: 26135914]

METHODS AND RESULTS:
Six new C21 steroidal glycosides, cynotophyllosides A-F (1-6), together with 16 known compounds, were isolated from the roots of Cynanchum otophyllum. The structures of the new compounds were elucidated by spectroscopic analysis and chemical methods. The three major components, Otophylloside F (15), otophylloside B (17), and rostratamine 3-O-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-cymaropyranoside (18), suppressed the seizure-like locomotor activity caused by pentylenetetrazole in zebrafish.
CONCLUSIONS:
Preliminary structure-activity relation studies revealed that a pregnene skeleton with a C-12 ester group (ikemaoyl > cinnamoyl > hydroxy > p-hydroxybenzoyl) and a C-3 sugar chain consisting of three 2,6-dideoxysaccharide units is essential for this suppressive activity.

Product Name	Otophylloside F
Price:
CAS No.:	250217-73-3
Catalog No.:	CFN89258
Molecular Formula:	C₄₈H₇₆O₁₆
Molecular Weight:	909.11 g/mol
Purity:	>=98%
Type of Compound:	Steroids
Physical Desc.:	Powder
Source:	The roots of Cynanchum otophyllum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antiepileptogenic Compound Library Steroids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.1 mL	5.4999 mL	10.9998 mL	21.9995 mL	27.4994 mL
5 mM	0.22 mL	1.1 mL	2.2 mL	4.3999 mL	5.4999 mL
10 mM	0.11 mL	0.55 mL	1.1 mL	2.2 mL	2.7499 mL
50 mM	0.022 mL	0.11 mL	0.22 mL	0.44 mL	0.55 mL
100 mM	0.011 mL	0.055 mL	0.11 mL	0.22 mL	0.275 mL

CFN80437	Qingyangshengenin A	106644-33-1	933.09	C₄₉H₇₂O₁₇
CFN96087	Dregeoside A11	89020-11-1	1101.3	C₅₅H₈₈O₂₂
CFN89225	Otophylloside B 4'''-O-alpha-L-cymaropyranoside	171422-82-5	1067.31	C₅₆H₉₀O₁₉
CFN89237	Otophylloside B 4'''-O-beta-D-cymaropyranoside	171422-85-8	1067.31	C₅₆H₉₀O₁₉
CFN89226	Otophylloside B 4'''-O-beta-D-oleandropyranoside	168001-54-5	1067.31	C₅₆H₉₀O₁₉
CFN89036	Otophylloside O	1326583-08-7	1077.25	C₅₆H₈₄O₂₀
CFN96784	Cynatratoside A	97399-96-7	504.62	C₂₈H₄₀O₈
CFN96787	Glaucogenin C mono-D-thevetoside	849201-84-9	520.61	C₂₈H₄₀O₉
CFN95299	Glaucoside A	81474-91-1	520.2	C₂₈H₄₀O₉
CFN95300	Glaucoside C	81474-89-7	794.9	C₄₁H₆₂O₁₅