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    Phyperunolide E
    Phyperunolide E
    Information
    CAS No. 1198400-52-0 Price
    Catalog No.CFN96990Purity>=98%
    Molecular Weight520.61Type of CompoundSteroids
    FormulaC28H40O9Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Our products had been exported to the following research institutions and universities, And still growing.
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    Biological Activity
    Description: Phyperunolide E is a natural product from Physalis peruviana L.
    In vitro:
    Food Chemistry, 2009, 116(2):462-469.
    New cytotoxic withanolides from Physalis peruviana.[Reference: WebLink]

    METHODS AND RESULTS:
    Investigation of the extracts of Physalis peruviana L. has led to the isolation of seven new withanolides, phyperunolide A (1), phyperunolide B (2), phyperunolide C (3), phyperunolide D (4), peruvianoxide (5), Phyperunolide E (16), and phyperunolide F (17) together with ten known withanolides. The structure and absolute stereochemistry of all compounds were elucidated on the basis of CD and NMR spectral analysis, respectively.
    CONCLUSIONS:
    Compounds 1, 6, 7, and 9 showed cytotoxicity against lung cancer (A549), breast cancer (MDA-MB-231 and MCF7), and liver cancer (Hep G2 and Hep 3B) cancer cell lines. The presence of 5β,6β-epoxy-2-en-1-ones in withanolides is greatly helpful in cytotoxicity, it is a key known important factor to cytotoxicity; however, interestingly, the unusual 5-chloride withanolide, 9, displayed significant activity.
    Phyperunolide E Description
    Source: The fruits of Physalis peruviana L.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.9208 mL 9.6041 mL 19.2082 mL 38.4165 mL 48.0206 mL
    5 mM 0.3842 mL 1.9208 mL 3.8416 mL 7.6833 mL 9.6041 mL
    10 mM 0.1921 mL 0.9604 mL 1.9208 mL 3.8416 mL 4.8021 mL
    50 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.7683 mL 0.9604 mL
    100 mM 0.0192 mL 0.096 mL 0.1921 mL 0.3842 mL 0.4802 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.