Picraline | CAS:2671-32-1 | Manufacturer ChemFaces

Picraline

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

Betulonic acid

Catalog No: CFN98682
CAS No: 4481-62-3
Price: $40/20mg

Luteolin

Catalog No: CFN98784
CAS No: 491-70-3
Price: $40/20mg

Triptolide

Catalog No: CFN99196
CAS No: 38748-32-2
Price: $118/20mg

Scopolamine

Catalog No: CFN98200
CAS No: 51-34-3
Price: $/mg

Aromadendrene

Catalog No: CFN95074
CAS No: 489-39-4
Price: $40/20mg

L-Arginine

Catalog No: CFN90550
CAS No: 74-79-3
Price: $30/20mg

Benzoic acid

Catalog No: CFN97121
CAS No: 65-85-0
Price: $25/20mg

Tectorigenin

Catalog No: CFN99920
CAS No: 548-77-6
Price: $80/20mg

Oleic acid

Catalog No: CFN94800
CAS No: 112-80-1
Price: $30/20mg

Abietic acid

Catalog No: CFN90587
CAS No: 514-10-3
Price: $40/20mg

Picraline Description

Source:	The herbs of Rauvolfia verticillata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Bioorg Med Chem. 2010 Mar 15;18(6):2152-8.

Alstiphyllanines E-H, picraline and ajmaline-type alkaloids from Alstonia macrophylla inhibiting sodium glucose cotransporter.[Pubmed: 20189404]

METHODS AND RESULTS:
Three new Picraline-type alkaloids, alstiphyllanines E-G (1-3) and a new ajmaline-type alkaloid, alstiphyllanine H (4) were isolated from the leaves of Alstonia macrophylla together with 16 related alkaloids (5-20). Structures and stereochemistry of 1-4 were fully elucidated and characterized by 2D NMR analysis. Alstiphyllanines E and F (1 and 2) showed moderate Na(+)-glucose cotransporter (SGLT1 and SGLT2) inhibitory activity.
CONCLUSIONS:
A series of a hydroxy substituted derivatives 21-28 at C-17 of the Picraline-type alkaloids have been derived as having potent SGLT inhibitory activity. 10-Methoxy-N(1)-methylburnamine-17-O-veratrate (6) exhibited potent inhibitory activity, suggesting that the presence of an ester side chain at C-17 may be important to show SGLT inhibitory activity. Structure activity relationship of alstiphyllanines on inhibitory activity of SGLT was discussed.

Product Name	Picraline
Price:
CAS No.:	2671-32-1
Catalog No.:	CFN97888
Molecular Formula:	C₂₃H₂₆N₂O₅
Molecular Weight:	410.5 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The herbs of Rauvolfia verticillata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Alkaloids Compound Library SGLT Inhibitor Library

Description:	A series of a hydroxy substituted derivatives 21-28 at C-17 of the Picraline-type alkaloids have been derived as having potent SGLT inhibitory activity.
Targets:	SGLT

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.4361 mL	12.1803 mL	24.3605 mL	48.7211 mL	60.9013 mL
5 mM	0.4872 mL	2.4361 mL	4.8721 mL	9.7442 mL	12.1803 mL
10 mM	0.2436 mL	1.218 mL	2.4361 mL	4.8721 mL	6.0901 mL
50 mM	0.0487 mL	0.2436 mL	0.4872 mL	0.9744 mL	1.218 mL
100 mM	0.0244 mL	0.1218 mL	0.2436 mL	0.4872 mL	0.609 mL

CFN97900	Akuammiline	1897-26-3	394.5	C₂₃H₂₆N₂O₄
CFN96687	Rauvoyunine B	1414883-82-1	426.46	C₂₃H₂₆N₂O₆
CFN97938	Alstolenine	85769-33-1	546.6	C₃₁H₃₄N₂O₇
CFN97888	Picraline	2671-32-1	410.5	C₂₃H₂₆N₂O₅
CFN97966	Rauvoyunine C	1211543-01-9	592.7	C₃₂H₃₆N₂O₉
CFN97942	Pseudoakuammigine	2447-70-3	366.5	C₂₂H₂₆N₂O₃
CFN98013	Picralinal	20045-06-1	366.4	C₂₁H₂₂N₂O₄
CFN98700	Picrinine	4684-32-6	338.4	C₂₀H₂₂N₂O₃
CFN99260	N1-Methoxymethyl picrinine	1158845-78-3	382.5	C₂₂H₂₆N₂O₄
CFN97014	N-Demethylechitamine	60048-88-6	370.5	C₂₁H₂₆N₂O₄