|Source:||The herbs of Lindera strychnifolia|
|Biological Activity or Inhibitors:|| 1. Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose can moderately inhibit α-amylase activity, with the IC50 value of 0.03 umol/ml.
|Solvent:||DMSO, Pyridine, Methanol, Ethanol, etc.|
|Storage:||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
|After receiving:||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.|
|1 mg||5 mg||10 mg||20 mg||25 mg|
|1 mM||1.1459 mL||5.7293 mL||11.4587 mL||22.9174 mL||28.6467 mL|
|5 mM||0.2292 mL||1.1459 mL||2.2917 mL||4.5835 mL||5.7293 mL|
|10 mM||0.1146 mL||0.5729 mL||1.1459 mL||2.2917 mL||2.8647 mL|
|50 mM||0.0229 mL||0.1146 mL||0.2292 mL||0.4583 mL||0.5729 mL|
|100 mM||0.0115 mL||0.0573 mL||0.1146 mL||0.2292 mL||0.2865 mL|
J Ethnopharmacol. 2015 Apr 2;163:256-63.
|Evaluation of hypoglycemic effects of polyphenols and extracts from Penthorum chinense.[Pubmed: 25620384 ]|
|The Penthorum chinense extract possessed anti-hyperglycemic activities as shown by the decreased serum levels of glycosylated hemoglobulin A1C (HbA1c), triglyceride(TG), total cholesterol (TC), and low density lipoprotein-cholesterol (LDL-C), as well as increased serum levels of high density lipoprotein-cholesterol (HDL-C) and insulin. Penthorum chinense extract also improved the oral glucose tolerance test (OGTT) to a certain degree. Moreover, the OSTT study showed that in diabetic rats, the extract (600mg/kg) caused a significant hypoglycemic effect with a blood glucose reduction of 42% at 60min. To identify the active constituents, three polyphenols, pinocembrin-7-O-[4″,6″-hexahydroxydiphenoyl]-β-d-glucose (1), pinocembrin-7-O-[3″-O-galloyl-4″, 6″-hexahydroxydiphenoyl]-β- d-glucose (Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,2), and thonningianin A (3) were isolated from Penthorum chinense. Compounds 1-3 moderately inhibited α-amylase activity, with IC50 values of 0.14, 0.03, and 0.08μmol/ml, respectively.|