Preskimmianine | CAS:38695-41-9 | Manufacturer ChemFaces

Preskimmianine

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

Notoginsenoside R4

Catalog No: CFN91142
CAS No: 87741-77-3
Price: $238/5mg

Dehydroabietic acid

Catalog No: CFN99822
CAS No: 1740-19-8
Price: $40/20mg

Jatrorrhizine

Catalog No: CFN98493
CAS No: 3621-38-3
Price: $60/20mg

Eurycomanone

Catalog No: CFN92008
CAS No: 84633-29-4
Price: $268/20mg

3,7-Di-O-methylquercetin

Catalog No: CFN96221
CAS No: 2068-02-2
Price: $/mg

Vaccarin

Catalog No: CFN90131
CAS No: 53452-16-7
Price: $30/20mg

Tussilagone

Catalog No: CFN90629
CAS No: 104012-37-5
Price: $148/20mg

Ginsenoside Rb3

Catalog No: CFN99966
CAS No: 68406-26-8
Price: $70/20mg

Lanosterol

Catalog No: CFN92368
CAS No: 79-63-0
Price: $198/20mg

o-Methoxycinnamaldehyde

Catalog No: CFN93299
CAS No: 1504-74-1
Price: $40/20mg

Description:

Preskimmianine is the biogenetic precursor of skimmianine.It can significantly inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 cells.

Targets:

In vitro:

J Enzyme Inhib Med Chem. 2012 Aug;27(4):490-4

Inhibitory alkaloids from Dictamnus dasycarpus root barks on lipopolysaccharide-induced nitric oxide production in BV2 cells.[Pubmed: 21827366 ]

METHODS AND RESULTS:
The methanolic extract of Dictamnus dasycarpus root barks afforded one new glycosidic quinoline alkaloid, 3-[1β-hydroxy-2-(β-D-glucopyranosyloxy)-ethyl)-4-methoxy-2(1H)-quinolinone (1), together with nine known compounds, Preskimmianine (2), 8-methoxy-N-methylflindersine (3), dictamine (4), γ-fagarine (5), halopine (6), skimmianine (7), dictangustine-A (8), iso-γ-fagarine (9), isomaculosidine (10).
CONCLUSIONS:
The isolated alkaloids significantly inhibited nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 cells. Among them, compounds 3 and 7 showed the most potent inhibitory activities on LPS-induced NO production.

Preskimmianine Description

Source:	The root barks of Dictamnus dasycarpus.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Preskimmianine
Price:
CAS No.:	38695-41-9
Catalog No.:	CFN96377
Molecular Formula:	C₁₇H₂₁NO₄
Molecular Weight:	303.4 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The root barks of Dictamnus dasycarpus.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-inflammatory Compound Library Precursors Compound Library Alkaloids Compound Library NO Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.296 mL	16.4799 mL	32.9598 mL	65.9196 mL	82.3995 mL
5 mM	0.6592 mL	3.296 mL	6.592 mL	13.1839 mL	16.4799 mL
10 mM	0.3296 mL	1.648 mL	3.296 mL	6.592 mL	8.2399 mL
50 mM	0.0659 mL	0.3296 mL	0.6592 mL	1.3184 mL	1.648 mL
100 mM	0.033 mL	0.1648 mL	0.3296 mL	0.6592 mL	0.824 mL

CFN92735	N-Methylflindersine	50333-13-6	241.3	C₁₅H₁₅NO₂
CFN96256	Glycosolone	67879-81-6	273.3	C₁₆H₁₉NO₃
CFN96395	Zanthobungeanine	64190-94-9	271.3	C₁₆H₁₇NO₃
CFN91530	8-Methoxyflindersine	35989-00-5	257.3	C₁₅H₁₅NO₃
CFN96377	Preskimmianine	38695-41-9	303.4	C₁₇H₂₁NO₄
CFN92396	3,4-Dihydro-6,7-(methylenedioxy)-2(1H)-quinolinone	94527-34-1	191.2	C₁₀H₉NO₃
CFN96151	Oxindole	59-48-3	133.2	C₈H₇NO
CFN96144	2-(4-Hydroxy-2-oxoindolin-3-yl)acetonitrile	1380540-77-1	188.2	C₁₀H₈N₂O₂
CFN97943	Griffithazanone A	240122-30-9	257.2	C₁₄H₁₁NO₄
CFN92334	Oxohydrastinine	552-29-4	205.2	C₁₁H₁₁NO₃