(+)-Rhododendrol | CAS:59092-94-3 | Manufacturer ChemFaces

(+)-Rhododendrol

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Description:

(+)-Rhododendrol shows anti-inflammatory effects, it can suppress the NO production by activated macrophages in vivo.

Targets:

In vivo:

Planta Med. 1998 Oct;64(7):598-602.

(+)-rhododendrol and epi-rhododendrin suppress the NO production by activated macrophages in vivo.[Pubmed: 9810263 ]

METHODS AND RESULTS:
In this study, we investigated the effect of (+)-Rhododendrol (1) and epi-rhododendrin (2) isolated from Acer nikoense Maxim. (Aceraceae) on nitric oxide (NO) production in mouse peritoneal macrophages elicited by bacillus Calmette-Guérin and in vitro stimulated by lipopolysaccharide. The NO production was not affected by an oral administration of methanol extract at a dose of 100 mg/kg/day. However, the AcOEt soluble fraction significantly reduced the NO production. (+)-Rhododendrol (1) isolated as an active substance from the AcOEt fraction suppressed the NO production. epi-Rhododendrin (2), the glucoside of (+)-Rhododendrol (1) isolated from the n-BuOH fraction, also suppressed the NO production.
CONCLUSIONS:
As NO is one of the critical mediators in inflammation, these results suggest that (+)-Rhododendrol (1) and epi-rhododendrin (2) contribute in part to the anti-inflammatory effect of A. nikoense.

(+)-Rhododendrol Description

Source:	The plants of Acer nikoense Maxim.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	(+)-Rhododendrol
Price:
CAS No.:	59092-94-3
Catalog No.:	CFN96789
Molecular Formula:	C₁₀H₁₄O₂
Molecular Weight:	166.22 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Oil
Source:	The plants of Acer nikoense Maxim.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anti-inflammatory Compound Library Phenols Compound Library NO Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	6.0161 mL	30.0806 mL	60.1612 mL	120.3225 mL	150.4031 mL
5 mM	1.2032 mL	6.0161 mL	12.0322 mL	24.0645 mL	30.0806 mL
10 mM	0.6016 mL	3.0081 mL	6.0161 mL	12.0322 mL	15.0403 mL
50 mM	0.1203 mL	0.6016 mL	1.2032 mL	2.4064 mL	3.0081 mL
100 mM	0.0602 mL	0.3008 mL	0.6016 mL	1.2032 mL	1.504 mL

CFN89239	1,7-Dihydroxy-2,3-dimethoxyxanthone	78405-33-1	288.25	C₁₅H₁₂O₆
CFN93038	Pseudoprotogracillin	637349-03-2	1047.2	C₅₁H₈₂O₂₂
CFN90173	Ginkgetin	481-46-9	566.51	C₃₂H₂₂O₁₀
CFN98959	Stigmasta-5,8-dien-3-ol	570-72-9	412.7	C₂₉H₄₈O