Rhuscholide A | CAS:944804-58-4 | Manufacturer ChemFaces

Rhuscholide A

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Description:

Rhuscholide A possesses significant anti-HIV-1 activity with an EC50 value of 1.62 microM and a therapeutic index (TI) of 42.40.

Targets:

HIV

In vitro:

Planta Med. 2007 Mar;73(3):279-82.

A new benzofuranone and anti-HIV constituents from the stems of Rhus chinensis.[Pubmed: 17290322]

METHODS AND RESULTS:
A new benzofuran lactone, Rhuscholide A (1), was isolated from the stems of RHUS CHINENSIS, together with six known compounds.Based on 1D, 2D NMR (COSY, HMQC, HMBC) and mass (EI-MS, HR-EI-MS) spectral data, the structure of Rhuscholide A was deduced to be 5-hydroxy-3-(propan-2-ylidene)-7-(3,7,11,15-tetramethylhexadeca-2,6,10,11-tetraenyl)-2(3 H)-benzofuranone (1).
CONCLUSIONS:
Anti-HIV-1 bioassays IN VITRO revealed that Rhuscholide A possesses significant anti-HIV-1 activity with an EC50 value of 1.62 microM and a therapeutic index (TI) of 42.40.

Rhuscholide A Description

Source:	The stems of Rhus chinensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Rhuscholide A
Price:
CAS No.:	944804-58-4
Catalog No.:	CFN97526
Molecular Formula:	C₃₁H₄₂O₃
Molecular Weight:	462.7 g/mol
Purity:	>=98%
Type of Compound:	Miscellaneous
Physical Desc.:	Powder
Source:	The stems of Rhus chinensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antiviral Compound Library Miscellaneous Compound Library HIV Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.1612 mL	10.8061 mL	21.6123 mL	43.2246 mL	54.0307 mL
5 mM	0.4322 mL	2.1612 mL	4.3225 mL	8.6449 mL	10.8061 mL
10 mM	0.2161 mL	1.0806 mL	2.1612 mL	4.3225 mL	5.4031 mL
50 mM	0.0432 mL	0.2161 mL	0.4322 mL	0.8645 mL	1.0806 mL
100 mM	0.0216 mL	0.1081 mL	0.2161 mL	0.4322 mL	0.5403 mL

CFN90099	3-Nitro-1-(4-octylphenyl)-1-propanone	899822-97-0	291.39	C₁₇H₂₅NO₃
CFN90100	3-(Hydroxymethyl)-3-nitro-1-(4-octylphenyl)-1,4-butanediol	899822-99-2	353.45	C₁₉H₃₁NO₅
CFN90103	1-Octanone,1-[4-[2-(acetyloxy)ethyl]phenyl]	162358-03-4	290.39	C₁₈H₂₆O₃
CFN90104	Benzeneethanol, 4-octyl-, 1-acetate	162358-04-5	276.41	C₁₈H₂₈O₂
CFN90105	1-(2-iodoethyl)-4-octylbenzene	162358-07-8	344.27	C₁₆H₂₅I
CFN90106	Acetamide, N-[1,1-bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]-	162358-09-0	433.3	C₂₅H₃₉NO₅
CFN90108	Benzeneethanol, 4-octyl	162358-05-6	234.38	C₁₆H₂₆O
CFN97526	Rhuscholide A	944804-58-4	462.7	C₃₁H₄₂O₃
CFN90071	1-Phenyloctane	2189-60-8	190.32	C₁₄H₂₂
CFN90097	3-Chloro-1-(4-octylphenyl)-propanone	928165-59-7	280.83	C₁₇H₂₅ClO