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    Ruixianglangdusu B
    Ruixianglangdusu B
    Information
    CAS No. 447454-49-1 Price
    Catalog No.CFN96558Purity>=98%
    Molecular Weight584.57Type of CompoundFlavonoids
    FormulaC33H28O10Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Ruixianglangdusu B Description
    Source: The roots of Stellera chamaejasme L.
    Biological Activity or Inhibitors: 1. Ruixianglangdusu B exhibits immunomodulatory activity.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7107 mL 8.5533 mL 17.1066 mL 34.2132 mL 42.7665 mL
    5 mM 0.3421 mL 1.7107 mL 3.4213 mL 6.8426 mL 8.5533 mL
    10 mM 0.1711 mL 0.8553 mL 1.7107 mL 3.4213 mL 4.2766 mL
    50 mM 0.0342 mL 0.1711 mL 0.3421 mL 0.6843 mL 0.8553 mL
    100 mM 0.0171 mL 0.0855 mL 0.1711 mL 0.3421 mL 0.4277 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Ruixianglangdusu B References Information
    Citation [1]

    Yao Xue Xue Bao. 2001 Sep;36(9):669-71.

    New biflavanones and bioactive compounds from Stellera chamaejasme L.[Pubmed: 12580104]
    To study the chemical constituents of the root of Stellera chamaejasme L. METHODS: Various column chromatographies on silica gel and RP-18 were employed for isolation and purification. Structures of compounds were elucidated by spectral analysis. RESULTS: Eight lignans and three biflavonoids possessing a C-3/C-3" linkage were isolated. They are ruixianglangdusu A (1) and Ruixianglangdusu B (2), 4',4'",5,5",7,7"-hexahydroxy-3,3"-biflavone (3), (+)-kusunokinin (4), lirioresinol-B (5), magnolenin C (6), (-)-pinoresinol monomethyl ether (7), (-)-pinoresinol (8), (+)-matairesinol (9), isohinokinin (10) and (-)-eudesmin (11). CONCLUSION: Compounds 1 and 2 are new biflavanones, 1 is enantiomeric to known chamaejasmenin C, 4, 6, 8, 9, 10 and 11 were isolated from this plant for the first time, and 7 was isolated from natural resources for the first time. In vitro bioassays showed that 3 and 8 exhibited antibacterial activity, and 1, 2, 9 and 11 exhibited immunomodulatory activity.