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Saikosaponin I
Saikosaponin I
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Saikosaponin I
Price:
CAS No.: 103629-71-6
Catalog No.: CFN93143
Molecular Formula: C48H78O17
Molecular Weight: 927.13 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Bupleurum chinense DC.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Saikosaponin I shows strong inhibition activity against influenza virus WSN33.
Targets: Antifection
Saikosaponin I Description
Source: The herbs of Bupleurum chinense DC.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0786 mL 5.393 mL 10.786 mL 21.5719 mL 26.9649 mL
5 mM 0.2157 mL 1.0786 mL 2.1572 mL 4.3144 mL 5.393 mL
10 mM 0.1079 mL 0.5393 mL 1.0786 mL 2.1572 mL 2.6965 mL
50 mM 0.0216 mL 0.1079 mL 0.2157 mL 0.4314 mL 0.5393 mL
100 mM 0.0108 mL 0.0539 mL 0.1079 mL 0.2157 mL 0.2696 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
China Journal of Chinese Materia Medica, 2016, 41(7):1251.
Triterpenoid saponins from Bupleurum marginatum var. stenophyllum.[Pubmed: 28879740]

METHODS AND RESULTS:
Twelve compounds were obtained by phytochemical investigation of 70% EtOH ( containing 0.5%NH3•H2O )extract of the roots of Bupleurum marginatum var. stenophyllum. Based on comparison of their spectral data, including HR-ESI-MS, ¹H-NMR, ¹³C-NMR data, with those of the literature, their structures were elucidated as saikosaponin b2 (1), saikosaponin a(2), saikosaponin b1(3), saikosaponin d (4), hydroxysaikosaponin a (5), saikosaponin b3 (6), saikosaponin c(7),Saikosaponin I(8), saikosaponin f (9), chikusaikosides Ⅱ(10), saikosaponin s (11), and Saikosaponin I(12).
CONCLUSIONS:
All compounds belong to olean-type triterpenoid saponin and compounds 1, 3, 5, 8-9,11, and 12 were isolated from this plant for the first time. At a concentration of 20 μmol•L⁻¹, compounds 2, 4, 6, 8, 11 and 12 showed strong inhibition activity against influenza virus WSN33 with the inhibition rate of 91.3%,88.6%,53.4%,61.3%,77.3% and 57.4%,respectively.
Luteolin 7-rutinoside

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CAS No: 20633-84-5
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Daidzin

Catalog No: CFN99101
CAS No: 552-66-9
Price: $40/20mg
Taraxasterol

Catalog No: CFN99074
CAS No: 1059-14-9
Price: $338/20mg
Isovitexin 2''-O-arabinoside

Catalog No: CFN90943
CAS No: 53382-71-1
Price: $318/10mg
Emodin-8-beta-D-glucoside

Catalog No: CFN99572
CAS No: 23313-21-5
Price: $118/20mg
Inokosterone

Catalog No: CFN92515
CAS No: 15130-85-5
Price: $ / mg
Xanthotoxol

Catalog No: CFN98016
CAS No: 2009-24-7
Price: $30/20mg
Platycoside E

Catalog No: CFN90786
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Price: $ / mg
Hederagenin

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Price: $30/20mg
Hesperidin

Catalog No: CFN98839
CAS No: 520-26-3
Price: $30/20mg
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