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Schizanrin L
Schizanrin L
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Schizanrin L
Price:
CAS No.: 874472-16-9
Catalog No.: CFN92714
Molecular Formula: C31H36O8
Molecular Weight: 536.6 g/mol
Purity: >=98%
Type of Compound: Lignans
Physical Desc.: Cryst.
Source: The herbs of Kadsura coccinea
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Instytut Nawozów Sztucznych w ... (Poland)
  • Lodz University of Technology (Poland)
  • Universiti Putra Malaysia(UPM) (Malaysia)
  • Universidad de Antioquia (Colombia)
  • University of Melbourne (Australia)
  • Florida A&M University (USA)
  • University of Bonn (Germany)
  • Kitasato University (Japan)
  • University of Madras (India)
  • Shanghai Institute of Organic C... (China)
  • Semmelweis Unicersity (Hungary)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Schizanrin L is a natural product from Kadsura coccinea.
In vitro:
Planta Med. 2005 Jul;71(7):646-53.
Antihepatitis activity (anti-HBsAg and anti-HBeAg) of C19 homolignans and six novel C18 dibenzocyclooctadiene lignans from Kadsura japonica.[Pubmed: 16041651 ]

METHODS AND RESULTS:
Bioassay-directed fractionation of the EtOAc extract of Kadsura japonica has led to the isolation of six new C18 dibenzocyclooctadiene lignans, schizanrin I, schizanrin J, schizanrin K, Schizanrin L, schizanrin M, schizanrin N, along with four known C19 homolignans, taiwanschirins A, B, C, and heteroclitin F. The elucidations of the new structures were based on spectral analysis.
CONCLUSIONS:
Bioassay evaluation against human type B hepatitis revealed that taiwanschirins A and B showed strong activity for anti-HBsAg and a medium effect for anti-HBeAg at 25 microg/mL (12.9 and 11.9 microM for taiwanschirins A and B, respectively).
Schizanrin L Description
Source: The herbs of Kadsura coccinea
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8636 mL 9.3179 mL 18.6359 mL 37.2717 mL 46.5896 mL
5 mM 0.3727 mL 1.8636 mL 3.7272 mL 7.4543 mL 9.3179 mL
10 mM 0.1864 mL 0.9318 mL 1.8636 mL 3.7272 mL 4.659 mL
50 mM 0.0373 mL 0.1864 mL 0.3727 mL 0.7454 mL 0.9318 mL
100 mM 0.0186 mL 0.0932 mL 0.1864 mL 0.3727 mL 0.4659 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Citric acid

Catalog No: CFN98551
CAS No: 77-92-9
Price: $30/20mg
Orobol

Catalog No: CFN98737
CAS No: 480-23-9
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Pterostilbene

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Sakakin

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Price: $40/20mg
(-)-Epigallocatechin(EGC)

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Trigonelline

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