Senkyunolide | CAS:63038-10-8 | Manufacturer ChemFaces

Senkyunolide

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $27.4 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Reference standards.

In vitro:

Chinese Journal of Pharmaceutical Analysis, 2012, 32(9):1644-1647.

HPLC determination of equilibrium solubility and apparent oil/water partition coefficient of senkyunolide.[Reference: WebLink]

To determine the equilibrium solubility of senkyunoide and its partition coefficients for the n-octanol-water/buffer solution systems,so as to provide a basis for new formulations designing.
METHODS AND RESULTS:
A high performance liquid chromatography method was established to detect the concentration of Senkyunolide .The Megres ODS(5 μm,4.6 mm×100 mm)column was adopted,the mobile phase was acetonitrile-water(1:3, v/v)at a flow rate of 1.0 mL·min-1,and the detection wavelength was 278 nm.The concentration of Senkyunolide in different pH solutions and the partition coefficients for the n-octanol-water and n-octanol-buffer solution systems were detected. The equilibrium solubility reached a maximum of 34.31 mg·mL-1in water at 37°C.Senk yunolide was instable in solvent systems pH≥9.0.Partition coefficient of Senkyunolidewas 13.43(lg P app=1.13) in the n-octanol-water system;there was no significant effect of pH to partition coefficient of Senkyunolide .
CONCLUSIONS:
The study showed that Senkyunolide is soluble,the partition coefficient of Senkyunolide is moderate,and the relative molecular mass of Senkyunolide is small.Therefore,we can explain why Senkyunolide can quickly reach into blood and brain.Senkyunolide can be predicted with a good application value.

Senkyunolide Description

Source:	The roots of Ligusticum chuanxiong hort
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Senkyunolide
Price:	$118 / 20mg
CAS No.:	63038-10-8
Catalog No.:	CFN80253
Molecular Formula:	C₁₂H₁₆O₂
Molecular Weight:	192.11 g/mol
Purity:	>=98%
Type of Compound:	Miscellaneous
Physical Desc.:	Oil
Source:	The roots of Ligusticum chuanxiong hort
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Miscellaneous Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	5.2054 mL	26.0268 mL	52.0535 mL	104.107 mL	130.1338 mL
5 mM	1.0411 mL	5.2054 mL	10.4107 mL	20.8214 mL	26.0268 mL
10 mM	0.5205 mL	2.6027 mL	5.2054 mL	10.4107 mL	13.0134 mL
50 mM	0.1041 mL	0.5205 mL	1.0411 mL	2.0821 mL	2.6027 mL
100 mM	0.0521 mL	0.2603 mL	0.5205 mL	1.0411 mL	1.3013 mL

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CFN96784	Cynatratoside A	97399-96-7	504.62	C₂₈H₄₀O₈
CFN92538	4,6-Dimethoxy-2H-1-benzopyran-2-one	53666-78-7	206.2	C₁₁H₁₀O₄
CFN90679	Orcinol gentiobioside	164991-86-0	448.42	C₁₉H₂₈O₁₂