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Spiraline
Spiraline
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Spiraline
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CAS No.: 77156-25-3
Catalog No.: CFN00400
Molecular Formula: C22H33NO9
Molecular Weight: 455.50 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Parsonsia heterophylla A. Cunn.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
Spiraline Description
Source: The herbs of Parsonsia heterophylla A. Cunn.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1954 mL 10.9769 mL 21.9539 mL 43.9078 mL 54.8847 mL
5 mM 0.4391 mL 2.1954 mL 4.3908 mL 8.7816 mL 10.9769 mL
10 mM 0.2195 mL 1.0977 mL 2.1954 mL 4.3908 mL 5.4885 mL
50 mM 0.0439 mL 0.2195 mL 0.4391 mL 0.8782 mL 1.0977 mL
100 mM 0.022 mL 0.1098 mL 0.2195 mL 0.4391 mL 0.5488 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Tetrahedron Letters, 1980, 21(27):2657–2660.
Unusual macrocyclic pyrrolizidine alkaloids from Parsonsia heterophylla A. Cunn and Parsonsia spiralis Wall. (Apocynaceae).[Reference: WebLink]

METHODS AND RESULTS:
The isolation and/or characterization are reported of a series of 5 pyrrolizidine alkaloids, viz. parsonsine, its polymorphic form heterophylline, Spiraline, spiranine and spiracine.
CFN00362Crosemperine30785-56-9367.44C19H29NO6
CFN00364Crotalarine53937-97-6353.41C18H27NO6
CFN00369Erucifoline40158-95-0349.38C18H23NO6
CFN00453Erucifolin N-oxide123864-94-8365.4C18H23NO7
CFN00375Jacobine6870-67-3351.40C18H25NO6
CFN00461Jacobine N-oxide38710-25-7367.4C18H25NO7
CFN00380Madurensine26126-78-3351.40C18H25NO6
CFN00382Spiranine77156-23-1469.53C23H35NO9
CFN00385Monocrotaline N-oxide35337-98-5341.36C16H23NO7
CFN00386Spectabiline520-55-8367.40C18H25NO7
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