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Spiramine A
Spiramine A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Spiramine A
Price:
CAS No.: 114531-28-1
Catalog No.: CFN99243
Molecular Formula: C24H33NO4
Molecular Weight: 399.5 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Spiraea japonica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Standard reference
In vitro:
J Nat Prod. 2009 Apr;72(4):645-9.
Approach to the biosynthesis of atisine-type diterpenoid alkaloids.[Pubmed: 19275222]

METHODS AND RESULTS:
To determine the biosynthesis pathway of the atisine-type diterpenoid alkaloids Spiramine A/B and C/D, feeding experiments in in vitro cultured plantlets and enzymatic transformations in cell-free extracts were performed in combination with LCMS and tandem MS analyses. L-[2-(13)C,(15)N]Serine was used in the feeding experiments and enzymatic transformations, and the diterpene spiraminol was identified as a biosynthetic precursor of Spiramine Alkaloids. The LCMS and tandem MS spectra of the extracts from these experiments indicated that L-[2-(13)C,(15)N]serine was incorporated into Spiramine A/B and C/D.
CONCLUSIONS:
The labeled reaction products show that l-serine is the one possible nitrogen source involved in the biosynthesis of atisine-type DAs.
Spiramine A Description
Source: The herbs of Spiraea japonica
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.5031 mL 12.5156 mL 25.0313 mL 50.0626 mL 62.5782 mL
5 mM 0.5006 mL 2.5031 mL 5.0063 mL 10.0125 mL 12.5156 mL
10 mM 0.2503 mL 1.2516 mL 2.5031 mL 5.0063 mL 6.2578 mL
50 mM 0.0501 mL 0.2503 mL 0.5006 mL 1.0013 mL 1.2516 mL
100 mM 0.025 mL 0.1252 mL 0.2503 mL 0.5006 mL 0.6258 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Price: $40/20mg
Benzoylpaeoniflorin

Catalog No: CFN99536
CAS No: 38642-49-8
Price: $80/20mg
Calycosin

Catalog No: CFN99140
CAS No: 20575-57-9
Price: $80/20mg
Scutellarin

Catalog No: CFN99112
CAS No: 27740-01-8
Price: $30/20mg
Cinnamic aldehyde

Catalog No: CFN90321
CAS No: 14371-10-9
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Luteolin-6-C-glucoside

Catalog No: CFN98137
CAS No: 4261-42-1
Price: $128/20mg
Schisandrol A

Catalog No: CFN99012
CAS No: 7432-28-2
Price: $30/20mg
Militarine

Catalog No: CFN90409
CAS No: 58139-23-4
Price: $118/20mg
p-Hydroxy-cinnamic acid

Catalog No: CFN98179
CAS No: 7400-08-0
Price: $70/20mg
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