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Stauntosaponin A
Stauntosaponin A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Stauntosaponin A
Price:
CAS No.: 1417887-91-2
Catalog No.: CFN96658
Molecular Formula: C28H38O7
Molecular Weight: 486.60 g/mol
Purity: >=98%
Type of Compound: Steroids
Physical Desc.: Powder
Source: The herbs of Cynanchum stauntonii (Decne.) Schltr.ex Levl.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.
Targets: Sodium Channel | ATPase | Potassium Channel
In vitro:
Phytochemistry Letters, 2012, 5(2):304-308.
Two secopregnane-type steroidal glycosides from Cynanchum stauntonii (Decne.) Schltr.ex Levl.[Reference: WebLink]

METHODS AND RESULTS:
Two new steroid glycosides, Stauntosaponin A (1) and stauntosaponin B (2), were isolated from Cynanchum stauntonii (Decne.) Schltr.ex Levl. (Asclepiadaceae) together with five known compounds, anhydrohirundigenin monothevetoside, glaucogenin C mono-d-thevetoside, hirundoside A, cynatratoside A, and glaucogenin C. Stauntosaponins A and B were formulated as 3-O-β-d-oleandropyranosyl-14, 16: 15, 20: 18, 20-triepoxy-14, 15-secopregn-4, 6, 8(14)-triene (1) and 3-O-β-d-thevetopyranosyl-14, 16: 15, 20: 18, 20-triepoxy-14, 15-secopregn-4, 6, 8(14)-triene (2).
CONCLUSIONS:
Compounds 1 and 2 showed moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 μM, respectively, whereas ouabain as a positive control displayed an IC50 value of 3.5 μM.
Stauntosaponin A Description
Source: The herbs of Cynanchum stauntonii (Decne.) Schltr.ex Levl.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

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doi: 10.1016/j.molcel.2017.10.022.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0551 mL 10.2754 mL 20.5508 mL 41.1015 mL 51.3769 mL
5 mM 0.411 mL 2.0551 mL 4.1102 mL 8.2203 mL 10.2754 mL
10 mM 0.2055 mL 1.0275 mL 2.0551 mL 4.1102 mL 5.1377 mL
50 mM 0.0411 mL 0.2055 mL 0.411 mL 0.822 mL 1.0275 mL
100 mM 0.0206 mL 0.1028 mL 0.2055 mL 0.411 mL 0.5138 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Ginkgolic acid C17:1

Catalog No: CFN98508
CAS No: 111047-30-4
Price: $218/20mg
Cyclo(Pro-Leu)

Catalog No: CFN90281
CAS No: 5654-86-4
Price: $238/10mg
Gancaonin N

Catalog No: CFN95066
CAS No: 129145-52-4
Price: $463/5mg
Orientin

Catalog No: CFN98136
CAS No: 28608-75-5
Price: $70/20mg
p-Hydroxy-cinnamic acid

Catalog No: CFN98179
CAS No: 7400-08-0
Price: $70/20mg
Flavokawain C

Catalog No: CFN90741
CAS No: 56798-34-6
Price: $238/10mg
Tangeretin

Catalog No: CFN90240
CAS No: 481-53-8
Price: $30/20mg
Alloimperatorin

Catalog No: CFN93037
CAS No: 642-05-7
Price: $298/10mg
3,7-Di-O-methylquercetin

Catalog No: CFN96221
CAS No: 2068-02-2
Price: $/mg
Complanatoside B

Catalog No: CFN80156
CAS No: 142473-99-2
Price: $218/10mg
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