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Taxinine J
Taxinine J
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Taxinine J
Price:
CAS No.: 18457-46-0
Catalog No.: CFN96635
Molecular Formula: C39H48O12
Molecular Weight: 708.80 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The stem barks of Taxus sumatrana.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Taxinine J possesses inhibitory activity on heptoma cell in vitro.
In vitro:
Acta Chimica Sinica, 1988, 46(10):1053-1054.
Studies on the Diterpenes of Taxus Mairei——Ⅱ.Structure of 2-Deacetoxy-taxinine J[Reference: WebLink]

METHODS AND RESULTS:
A new taxane diterpene 5 and known Taxinine J(4)have been isolated from thebark of Taxus mairei(Lemée et Lévl.)S.Y.Hu collected in Fujian Province.The stucture of 5 was determined on the basis of spectral analysis.
CONCLUSIONS:
Both 4 and 5were shown to possess inhibitory activity on heptoma cell in vitro.
Taxinine J Description
Source: The stem barks of Taxus sumatrana.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.4108 mL 7.0542 mL 14.1084 mL 28.2167 mL 35.2709 mL
5 mM 0.2822 mL 1.4108 mL 2.8217 mL 5.6433 mL 7.0542 mL
10 mM 0.1411 mL 0.7054 mL 1.4108 mL 2.8217 mL 3.5271 mL
50 mM 0.0282 mL 0.1411 mL 0.2822 mL 0.5643 mL 0.7054 mL
100 mM 0.0141 mL 0.0705 mL 0.1411 mL 0.2822 mL 0.3527 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chemistry of Natural Compounds, 2015, 51(3):1-4.
Taxusumatrin, a New Taxoid from the Stem Bark of Taxus sumatrana.[Reference: WebLink]

METHODS AND RESULTS:
A new taxoid, taxusumatrin (1), has been isolated from the stem bark of Taxus sumatrana, together with six known compounds, Taxinine J (2), baccatin VI (3), 2α,5α,7β,10β-tetraacetoxy-taxa-4(20),11-diene (4), β-sitosterol (5), β-sitostenone (6), and 6β-hydroxystigmast-4-en-3-one (7).
CONCLUSIONS:
The structure of new compound 1 was determined through spectroscopic and MS analyses.
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Price: $318/5mg
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