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Tetraethoxypropane
Tetraethoxypropane
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Tetraethoxypropane
Price: $30 / 20mg
CAS No.: 122-31-6
Catalog No.: CFN90064
Molecular Formula: C11H24O4
Molecular Weight: 220.31 g/mol
Purity: >=98%
Type of Compound: Miscellaneous
Physical Desc.: Liquid
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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Size /Price /Stock 10 mM * 1 mL in DMSO / $8.9 / In-stock
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Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 1,1,3,3-Tetraethoxypropane,the precursor of the ubiquitous natural compound malondialdehyde. Tetraethoxypropane as the standard in the thiobarbituric acid (TBA) assay.
In vitro:
J Appl Toxicol. 2003 Sep-Oct;23(5):363-9.
Effect of quercetin and genistein on copper- and iron-induced lipid peroxidation in methyl linolenate.[Pubmed: 12975775]
The single and combined effects of two abundant flavonoids, namely quercetin and genistein, were investigated according to their ability to inhibit the oxidation of methyl linolenate via Fenton's pathway.
METHODS AND RESULTS:
Antioxidative activity was determined by oxidizing methyl linolenate suspended in a buffer solution with either Fe2+ (50 microM) or Cu2+ (50 microM) and hydrogen peroxide (0.01 mM) without or with a flavonoid sample (10 or 20 microM). Lipid peroxidation products were measured by the thiobarbituric acid (TBA) assay and the amounts of thiobarbituric acid-reactive substances (TBARS) were calculated from a calibration curve using 1,1,3,3-Tetraethoxypropane as the standard. Both quercetin and genistein at the 10 or 20 microM level decreased lipid peroxidation significantly compared with their respective controls. Of the two flavonoids tested, quercetin had a more marked effect on inhibiting lipid peroxides. Peroxidation products for the control samples were higher for the Fe2+-treated samples compared with the Cu2+ samples. Combination of both flavonoids at the same dose levels continued to decrease lipid peroxidation, the effect being the same for both metal ions.
CONCLUSIONS:
The data suggest that the combined flavonoids offered better protection than the single treatments and this may be attributed to the better radical scavenging or increased chelating capabilities of the combined over the single treatments. The differences in peroxide levels for the single treatment of quercetin compared with the genistein-treated samples may reflect the structural differences between these compounds in combating oxidative stress.
Tetraethoxypropane Description
Source:
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.5391 mL 22.6953 mL 45.3906 mL 90.7812 mL 113.4765 mL
5 mM 0.9078 mL 4.5391 mL 9.0781 mL 18.1562 mL 22.6953 mL
10 mM 0.4539 mL 2.2695 mL 4.5391 mL 9.0781 mL 11.3476 mL
50 mM 0.0908 mL 0.4539 mL 0.9078 mL 1.8156 mL 2.2695 mL
100 mM 0.0454 mL 0.227 mL 0.4539 mL 0.9078 mL 1.1348 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Journal of Labelled Compounds & Radiopharmaceuticals, 1985, 22(11):1175-9.
Synthesis of malondialdehyde-1-2H and malondialdehyde-1,3-2H2[Reference: WebLink]
Two synthetic routes for deuterium labelling of 1,1,3,3-Tetraethoxypropane, the precursor of the ubiquitous natural compound malondialdehyde, are described.
METHODS AND RESULTS:
In one scheme, deuterium is incorporated in ethyl vinyl ether by metalation with t-butyllithium followed by quenching with 2H2O. The conversion of the deuterated ether to monodeuterated Tetraethoxypropane, however, proceeds with an overall yield of only ˜5%. As an alternative route, we have metalated the bis-1,3-propylene dithioacetal of malondialdehyde which undergoes excellent deuterium incorporation (92%). In addition, the latter method allows isotopic labelling of either one or two deuterium(s) /molecule. Hydrolysis of the deuterated dithioacetal to the corresponding Tetraethoxypropane can be best effected by refluxing with HgO(red) /HgCl2/BF3. etherate in the presence of CH(OC2H5)3/C2H5OH. The overall yield of the method is 48%.
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