• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Natural Products
    Viroallosecurinine
    Viroallosecurinine
    Information
    CAS No. 1857-30-3 Price
    Catalog No.CFN96450Purity>=98%
    Molecular Weight217.27Type of CompoundAlkaloids
    FormulaC13H15NO2Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    Our products had been exported to the following research institutions and universities, And still growing.
  • Harvard University (USA)
  • Sant Gadge Baba Amravati Univers... (India)
  • University of Wuerzburg (Germany)
  • University of Brasilia (Brazil)
  • University of the Basque Country (Spain)
  • University of Limpopo (South Africa)
  • Utrecht University (Netherlands)
  • Universidade de Franca (Brazil)
  • University of Maryland School of... (USA)
  • University of Vienna (Austria)
  • Complutense University of Madrid (Spain)
  • More...
  • Package
    Featured Products
    Dihydrokavain

    Catalog No: CFN90536
    CAS No: 587-63-3
    Price: $318/20mg
    Desmethoxy yangonin

    Catalog No: CFN90149
    CAS No: 15345-89-8
    Price: $188/20mg
    Lanosterol

    Catalog No: CFN92368
    CAS No: 79-63-0
    Price: $388/5mg
    Butyrospermol

    Catalog No: CFN92376
    CAS No: 472-28-6
    Price: $388/5mg
    Gnetin D

    Catalog No: CFN92423
    CAS No: 84870-53-1
    Price: $468/5mg
    Viroallosecurinine Description
    Source: The roots of Securinega virosa
    Biological Activity or Inhibitors: 1. Virosecurinine and viroallosecurinine were isolated as two cytotoxic alkaloids from the leaves of Securinega virosa.
    2. Viroallosecurinine exhibits a MIC of 0.48 micrograms/ml for Pseudomonas aeruginosa and Staphylococcus aureus.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recent ChemFaces New Products and Compounds
    Acanthoside B

    Catalog No: CFN97220
    CAS No: 7374-79-0
    Price: $388/10 mg
    Deacetyl ganoderic acid F

    Catalog No: CFN90746
    CAS No: 100665-44-9
    Price: $218/5mg
    Glyasperin C

    Catalog No: CFN95065
    CAS No: 142474-53-1
    Price: $333/5mg
    3-Methoxyshancigusin I

    Catalog No: CFN95062
    CAS No: N/A
    Price: $413/5mg
    Ebracteolata cpd B

    Catalog No: CFN92882
    CAS No: 83459-37-4
    Price: $268/10mg
    Ganoderic acid B

    Catalog No: CFN92052
    CAS No: 81907-61-1
    Price: $328/10mg
    Suchilactone

    Catalog No: CFN95010
    CAS No: 50816-74-5
    Price: $338/5mg
    Ganoderic acid F

    Catalog No: CFN92055
    CAS No: 98665-15-7
    Price: $358/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.6026 mL 23.0128 mL 46.0257 mL 92.0514 mL 115.0642 mL
    5 mM 0.9205 mL 4.6026 mL 9.2051 mL 18.4103 mL 23.0128 mL
    10 mM 0.4603 mL 2.3013 mL 4.6026 mL 9.2051 mL 11.5064 mL
    50 mM 0.0921 mL 0.4603 mL 0.9205 mL 1.841 mL 2.3013 mL
    100 mM 0.046 mL 0.2301 mL 0.4603 mL 0.9205 mL 1.1506 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Viroallosecurinine References Information
    Citation [1]

    Nat Prod Res. 2007 Mar;21(3):234-42.

    Callus of Securinega suffruticosa, a cell line accumulates dextro Securinega alkaloids.[Pubmed: 17365714 ]
    Investigations on callus cultures of Securinega suffruticosa indicated that the cell line of S. suffruticosa callus was able to accumulate four known Securinega alkaloids with dextro rotation but not levo rotation as reported before: virosecurinine (1), Viroallosecurinine (2), 14,15-dihydrovirosecurinine (3) and ent-phyllanthidine (4). Time course studies on the growth of callus cultures were carried out. The effects of different plant growth regulators, sucrose concentrations on callus growth and virosecurinine production were also reported.
    Citation [2]

    J Pharm Sci. 1991 Apr;80(4):325-7.

    Cytotoxic principles of Securinega virosa: virosecurinine and viroallosecurinine and related derivatives.[Pubmed: 1865332]
    Virosecurinine (1) and Viroallosecurinine (2) were isolated as two cytotoxic alkaloids from the leaves of Securinega virosa. A comparison of the cytotoxicity of 1 and several of its derivatives indicates that an alpha,beta- and a gamma,delta-unsaturated lactone located in a strained ring system, such as rings -B, -C, and -D of 1, is structurally required for significant cytotoxicity.
    Citation [3]

    J Ethnopharmacol. 1990 Feb;28(1):129-33.

    Antibacterial activity of the leaves of Phyllanthus discoideus.[Pubmed: 2156112]
    The lyophilized aqueous extract (LWE) from the leaves of Phyllanthus discoideus was found to show an antibacterial activity. The alkaloid fraction obtained from LWE inhibited the growth of Escherichia coli and Enterococcus faecium (MIC = 1.6 mg/ml), Pseudomonas aeruginosa (MIC = 0.78 mg/ml), Staphylococcus aureus and Mycobacterium smegmatis (MIC = 0.2 mg/ml). Among the alkaloids identified, Viroallosecurinine and securinine showed a high activity. Viroallosecurinine exhibited a MIC of 0.48 micrograms/ml for Ps. aeruginosa and Staph. aureus. This alkaloid is bactericidal since the yields of MIC/MBC were less than 1. The MIC of securinine was 0.500 mg/ml for E. coli, Staph. aureus and Myc. smegmatis. These effects of Phyllanthus discoideus leaf extracts support some of the local uses of the plant in traditional therapy.