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    alpha-Isolupanine
    alpha-Isolupanine
    Information
    CAS No. 486-87-3 Price
    Catalog No.CFN91985Purity>=98%
    Molecular Weight248.36Type of CompoundAlkaloids
    FormulaC15H24N2OPhysical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    alpha-Isolupanine Description
    Source: The herbs of Sophora chrysophylla
    Biological Activity or Inhibitors:
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi:10.1016/j.phymed.2017.12.030

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.0264 mL 20.1321 mL 40.2641 mL 80.5283 mL 100.6603 mL
    5 mM 0.8053 mL 4.0264 mL 8.0528 mL 16.1057 mL 20.1321 mL
    10 mM 0.4026 mL 2.0132 mL 4.0264 mL 8.0528 mL 10.066 mL
    50 mM 0.0805 mL 0.4026 mL 0.8053 mL 1.6106 mL 2.0132 mL
    100 mM 0.0403 mL 0.2013 mL 0.4026 mL 0.8053 mL 1.0066 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    alpha-Isolupanine References Information
    Citation [1]

    J Nat Prod. 1999 Oct;62(10):1385-9.

    Detecting potential teratogenic alkaloids from blue cohosh rhizomes using an in vitro rat embryo culture.[Pubmed: 10543898]
    The novel alkaloid thalictroidine (1), as well as the known alkaloids taspine (2), magnoflorine (3), anagyrine (4), baptifoline (5), 5,6-dehydro-alpha-Isolupanine (6), alpha-Isolupanine (7), lupanine (8), N-methylcytisine (9), and sparteine (10), were identified from an extract of Caulophyllum thalictroides rhizomes. N-Methylcytisine exhibited teratogenic activity in the rat embryo culture (REC), an in vitro method to detect potential teratogens. The structure of 1 was elucidated using various spectroscopic methods, primarily by NMR techniques. Thalictroidine, anagyrine, and alpha-Isolupanine were not teratogenic in the REC at tested concentrations. Taspine (2) showed high embryotoxicity, but no teratogenic activity, in the REC.