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ent-3-Oxokaurane-16,17-diol
ent-3-Oxokaurane-16,17-diol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name ent-3-Oxokaurane-16,17-diol
Price:
CAS No.: 135683-73-7
Catalog No.: CFN99423
Molecular Formula: C20H32O3
Molecular Weight: 320.5 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Croton laevigatus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: AKaurane-3,16,17-triol,ent-kaurane-3-oxo-16α,17-diol,and ent-16α,17-dihydroxyatisan-3-one are three kinds of toxic diterpenoids isolated from the roots of genus Euphorbia.
ent-3-Oxokaurane-16,17-diol Description
Source: The herbs of Croton laevigatus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1201 mL 15.6006 mL 31.2012 mL 62.4025 mL 78.0031 mL
5 mM 0.624 mL 3.1201 mL 6.2402 mL 12.4805 mL 15.6006 mL
10 mM 0.312 mL 1.5601 mL 3.1201 mL 6.2402 mL 7.8003 mL
50 mM 0.0624 mL 0.312 mL 0.624 mL 1.248 mL 1.5601 mL
100 mM 0.0312 mL 0.156 mL 0.312 mL 0.624 mL 0.78 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chinese Journal of Natural Medicines,2010,8(2):101-3.
Diterpenes and triterpenes from the roots of Euphorbia fischeriana.[Reference: WebLink]
To study the terpenes in the roots of Euphorbia fischeriana.
METHODS AND RESULTS:
The compounds were isolated by silica gel column chromatography,and their structures were identified on the basis of physiochemical and spectral data. Eight diterpenes and four triterpenes were obtained from the ethyl acetate extract,and their structures were elucidated as jolkinolide A(1),jolkinolide B(2),prostratin(3),ent-kaurane-3-oxo-16α,17-diol(ent-3-Oxokaurane-16,17-diol,4),antiquorin(5),neriifolene(6),ent-atisane-3β,16α,17-triol(7),kauranoic acid(8),aleuritolic acid(9),24-methyl-enecy- cloartanol(10)and lupenyl acetate(11).
CONCLUSIONS:
Compounds 4-10 were isolated from this plant for the first time.
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Elemicin

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Price: $30/20mg
Glucoerucin

Catalog No: CFN00488
CAS No: 15592-37-7
Price: $ / mg
Sageone

Catalog No: CFN92166
CAS No: 142546-15-4
Price: $ / mg
Sophoraflavanone G

Catalog No: CFN92005
CAS No: 97938-30-2
Price: $138/20mg
Proline

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6,8-Diprenylgenistein

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8-Gingerol

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Physalin L

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Coelonin

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