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    Natural Products
    Catalog No. Information
    CFN99329 1,2-Benzenediol

    1. 1,2-Benzenediol(catechol) is used as 5% aq. soln. for photometric detn. of Nb, Os, Ta, Ti, W, complexing agent of some metals (e.g. Al, Ti) (anionic complexes associated with basic dyes).
    2. 1,2-Dihydroxybenzene can induce spontaneous convulsive activity in the anaesthetized mouse.
    3. 1,2-Dihydroxybenzene can produce myoclonic jerks in the rat.
    CFN90333 1,2-Dihydrotanshinquinone

    1. 1,2 Dihydrotanshinquinone is active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum.
    CFN99122 1,4-Dicaffeoylquinic acid

    1. 1,4-Dicaffeoylquinic acid has antioxidant activity.
    2. 1,4-Dicaffeoylquinic acid is a potent and highly selective class of HIV-1 integrase inhibitors, inhibitsHIV-1 replication in MT-2 cell culture at non-toxic concentrations.
    CFN99123 1,5-Dicaffeoylquinic acid

    1. 1,5-Dicaffeoylquinic acid has neuroprotective effects, it can prevent Aβ(42)-induced neurotoxicity through the activation of PI3K/Akt followed by the stimulation of Trk A, then the inhibition of GSK3β as well as the modulation of Bcl-2/Bax.
    2. 1,5-Dicaffeoylquinic acid has antioxidant activity, and is stronger than that of ascorbic acid.
    3. 1,5-Dicaffeoylquinic acid has protective effects against MPP~+ induces neurotoxicity of PC12 Cells, it (50 umol/L) pretreatment can inhibit the MPP+-induced up-regulation of the expression of α-synuclein mRNA and protein.
    4. 1, 5-Dicaffeoylquinic acid can mediate glutathione synthesis through activation of Nrf2 protects against OGD/reperfusion-induced oxidative stress in astrocytes.
    CFN99132 10-Gingerol

    1. 10-Gingerol has anti-neuroinflammatory capacity.
    2. 10-Gingerol effectively inhibits the growth of the oral pathogens, and inhibits exogenous ghrelin deacylation.
    3. 10-Gingerol induces [Ca2+]i rise by causing Ca2+ release from the endoplasmic reticulum and Ca2+ influx from non-L-type Ca2+ channels in SW480 cancer cells.
    4. 10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, c-Jun N-terminal kinase (JNK), p38 MAPK (p38), and extracellular signal-regulated kinase (ERK).
    CFN99736 10-Hydroxycamptothecin

    1. 10-Hydroxycamptothecin is an indole alkaloid isolated from a Chinese tree, Camptotheca acuminata, and has a wide spectrum of anticancer activity in vitro and in vivo mainly through inhibitory effects on topoisomerase I.
    2. 10-Hydroxycamptothecine can prevent fibroblast proliferation and epidural scar adhesion after laminectomy in rats.
    3. 10-Hydroxycamptothecin has antiangiogenic potential.
    CFN92300 10-Shogaol

    1. 10-Shogaol, as an antioxidant for human skin cell growth and a migration enhancer with potential to be a novel wound repair agent.
    2. 8- and 10-Shogaol have similar metabolic profiles to [6]-shogaol and exhibit similar toxicity toward human colon cancer cells.
    CFN90366 11-Hydroxy-sugiol

    CFN90152 11-Keto-beta-boswellic acid

    1. 11-Keto-beta-boswellic acid (KBA), one of the active constituents in the gum resin of Boswellia serrata, possesses significant anti-inflammatory activity.
    2. 11-Keto-beta-boswellic acid exerts multi-focal action in cancer cells while it required 10-fold higher the concentration to produce cytotoxicity in normal human PBMC and gingival cell line, and therefore, may find usefulness in the management of human leukemia.
    CFN96345 11-O-Galloylbergenin

    1. 11-O-Galloylbergenin shows significant analgesic activity at doses of 20 and 40 mg/kg against formalin test in rats, and it exhibits significant anti-inflammatory activity in carrageenan-induced paw edema model at doses of 10, 20 and 30 mg/kg.
    2. 11-O-Galloylbergenin shows good antioxidant and antiplasmodial activities, the EC50 values are 7.45±0.2 ug/mL and 5.39±0.28 ug/mL in DPPH antioxidant assay and reducing power assay respectively, while IC50 value for antiplasmodial assay is less than 2.5 uM.
    3. 11-O-Galloylbergenin shows significant urease inhibitory potential with IC50 value of 38.6±1.5 uM.