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    Natural Products
    Catalog No. Information
    CFN90576 3,29-Dibenzoyl karounitriol

    CFN90238 3,4,5-Tricaffeoylquinic acid

    1. 3,4,5-Tricaffeoylquinic acid may attenuate the TNF-α- and LPS-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like receptor 4 expression-mediated activation of the Akt, ERK and NF-ĸB pathways, it may exert an inhibitory effect against the pro-inflammatory mediator-induced skin disease.
    2. 3,4,5-Tricaffeoylquinic acid may attenuate the proteasome inhibitor-induced programmed cell death in PC12 cells by suppressing the activation of the mitochondrial pathway and the caspase-8- and Bid-dependent pathways, the effect be attributed to its inhibitory effect on the formation of reactive oxygen species and depletion of GSH.
    CFN99450 3,4-Dihydroxybenzaldehyde

    1. 3,4-dihydroxybenzaldehyde can scavenge DPPH radical, hydroxyl radical and intracellular ROS.
    2. 3,4-dihydroxybenzaldehyde chelated Fe2+.
    3. 3,4-dihydroxybenzaldehyde attenuated H2O2-induced cell death and apoptosis.
    4. 3,4-dihydroxybenzaldehyde inhibits oxidative DNA damage and its treatment decreased the expression level of phospho-H2A.X.
    5. Electrocatalysis of NADH Oxidation with Electropolymerized Films of 3,4-Dihydroxybenzaldehyde.
    CFN97568 3,4-Dihydroxybenzoic acid

    1. 3,4-Dihydroxybenzoic acid exhibits scavenging actions against the 1,1-diphenyl-2-picrylhydrazyl radical, the superoxide anion, and the hydroxyl radical.
    2. 3,4-Dihydroxybenzoic acid isolates from a green alga protects human keratinocytes against UVB-induced oxidative stress and apoptosis.
    3. The 3,4-Dihydroxybenzoic acid treatment resulted in 33.3, 65.0, 76.7 and 85.0% hatch inhibition at 0.125, 0.25, 0.5 and 1.0 mg/ml, respectively, 3 days after incubation.
    CFN90578 3,6'-Disinapoyl sucrose

    1. 3,6'-Disinapoyl sucrose has neuroprotective effect and antidepressive activity in rats, at least in part, by increasing expression of cyclic AMP response element (CRE)-binding protein (CREB) and its downstream target protein, brain-derived neurotrophic factor (BDNF).
    2. Treatment with 3,6'-Disinapoyl sucrose (0.6, 6, and 60 μmol/L) increases cell viability dose dependently, inhibits LDH release, and attenuated apoptosis. The mechanisms by which 3,6'-Disinapoyl sucrose protect neuron cells from glutamate-induced excitotoxicity include the downregulation of proapoptotic gene Bax and the upregulation of antiapoptotic gene Bcl-2.
    CFN99588 3-Butylidenephthalide

    1. (Z)-3-butylidenephthalide has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(50) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM.
    CFN92833 3-Deoxysappanchalcone

    1. 3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level.
    2. 3-Deoxysappanchalcone has anti-inflammatory effects, is a valuable compound for modulating inflammatory conditions.
    3. 3-Deoxysappanchalcone has anti-influenza virus activity, the mechanism involved anti-apoptosis and anti-inflammation activities in vitro.
    4. 3-Deoxysappanchalcone has inhibitory activity on MMP-9 expression and production in TNF-α-treated cells, is mediated by the suppression of AP-1 and NF-κB activation.
    CFN98851 3-Epicorosolic acid

    1. 3-Epicorosolic acid has antitumor activity.
    2. 3-Epicorosolic acid has anti-inflammatory activity.
    3. 3-Epicorosolic acid has a potent inhibitory effect on EBV-EA induction.
    4. 3-Epicorosolic acid shows mixed type inhibition against PTP1B, while it shows uncompetitive inhibition against α-glucosidase.
    CFN92743 3-Epidehydrotumulosic acid

    1. 3-Epidehydrotumulosic acid has inhibitory activity against AAPH-induced lysis of red blood cells.
    CFN96186 3'-Methoxydaidzein

    1. 3'-Methoxydaidzein and geraldol have antiplatelet aggregation activity and appear to be specific against collagen‐induce platelet aggregation with a IC50 values of12.3 and 61.5 uM, respectively.
    2. 3'-Methoxydaidzein has antioxidant activity.