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    ChemFaces is a professional high-purity natural products manufacturer.

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    Natural Products
    Catalog No. Information
    CFN92802 14-Deoxyandrographolide

    1. 14-Deoxyandrographolide desensitizes hepatocytes to TNF-alpha-mediated apoptosis through the release of TNFRSF1A.
    2. 14-Deoxyandrographolide has hepatoprotective activity, mediates activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS, may provide a promising approach in the prevention of liver diseases during chronic alcoholism.
    CFN92122 1-Acetyl-beta-carboline

    1. Combination of 1-acetyl-beta-carboline with ampicillin exhibits synergistic antibacterial activity against MRSA.
    CFN92600 1beta-Hydroxyalantolactone

    1. 1beta-Hydroxyalantolactone has protective effect against AD-like skin inflammation, can as a potential therapeutic agent for AD.
    CFN99121 1-Caffeoylquinic acid

    1. 1-Caffeoylquinic acid has anti-influenza activity.
    2. 1-Caffeoylquinic acid is an important intermediate in lignin biosynthesis.
    3. 1-Caffeoylquinic acid is an antioxidant, also slows the release of glucose into the bloodstream after a meal.
    CFN92374 1-Dehydro-10-gingerdione

    1. 1-Dehydro-10-gingerdione has anti-inflammatory action, the molecular target is Myeloid differentiation protein.
    2. 1-Dehydro-10-gingerdione involves in the suppression of NF-κB-regulated gene expression in LPS-activated macrophages, has therapeutic potential in NF-κB-associated inflammation and autoimmune disorders.
    CFN92298 1-Dehydro-6-gingerdione

    1. 1-Dehydro-6-gingerdione is 5-HT1A receptor partial agonists.
    2. 1-Dehydro-6-gingerdione has antioxidant and anti-inflammatory activities.
    3. 1-Dehydro-6-gingerdione significantly suppresses the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) proteins in a concentration-dependent fashion.
    CFN99933 1-Deoxynojirimycin

    1. 1-Deoxynojirimycin (DNJ), a potent glucosidase inhibitor, is beneficial for the suppression of abnormally high blood glucose levels and thereby prevention of diabetes mellitus, suggests that the newly developed DNJ-enriched powder can be used as a dietary supplement for preventing diabetes mellitus.
    2. 1-Deoxynojirimycin impairs oligosaccharide processing of alpha 1-proteinase inhibitor and inhibits its secretion in primary cultures of rat hepatocytes.
    3. 1-Deoxynojirimycin as a therapeutic agent by controlling the overgrowth and biofilm formation of S. mutans.
    4. 1-Deoxynojirimycin can block human immunodeficiency virus envelope glycoprotein- mediated membrane fusion at the CXCR4 binding step.
    CFN92123 1-Ethoxycarbonyl-beta-carboline

    CFN99076 2-(3,4-Dihydroxyphenyl)ethanol

    1. 2-(3,4-Dihydroxyphenyl)ethanol is a potent specific inhibitor of lipoxygenase activities, it inhibits platelet 12-LO activity (IC50, 4.2 microM) and PMNL 5-LO activity (IC50, 13 microM) but not cyclooxygenase activity in cell-free conditions; it also inhibits 12-LO activity in intact platelets (IC50, 50 microM) and reduces leukotriene B4 production in intact PMNL stimulated by A23187 (IC50, 26 microM).
    2. Hydroxytyrosol (2-(3,4dihydroxyphenyl)ethanol has antioxidant properties.
    CFN97462 2,3,24-Trihydroxy-12-ursen-28-oic acid

    1. 2α,3α,24-Trihydroxyurs-12-en-28-oic acid, a triterpenoid phytoalexin, isolated from peel of unripe fruits of nectarine (Prunus persica cv Fantasia), shows antifungal activity against the fungus mentioned.
    2. 2α,3α,24-Trihydroxyurs-12-en-28-oic acid shows in vitro cytotoxic activity against tumor cell lines including PLC,Hep3B,HepG2,HeLa,SW480,MCF-7 and Bel7402.