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    ChemFaces is a professional high-purity natural products manufacturer.

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    Natural Products
    Catalog No. Information
    CFN99131 8-Gingerol

    1. 8-Gingerol has antioxidant activity.
    2. 8-Gingerol has antimycobacterial activity.
    3. 8-Gingerol could be used as an effective skin-whitening agent.
    4. 8-Gingerol shows antipyretic and anti-inflammation characteristics.
    5. 8-Gingerol seems to be effective in an animal model of rheumatoid arthritis.
    6. 8-Gingerol inhibits the anti-serotonin 3 receptor function, exhibits cardiotonic activity.
    7. 8-Gingerol affects gastric motility and potentially have an antispasmodic effect on the gastrointestinal system.
    8. 8-gingerol inhibited melanogenesis in B16F10 and B16F1 cells by down-regulation of both mitogen-activated protein kinases (MAPK) and protein kinase A (PKA) signaling pathways or through its antioxidant properties.
    CFN98966 8-O-Acetylshanzhiside methyl ester

    1. 8-O-Acetylshanzhiside methyl ester has potent in vitro activity against respiratory syncytial virus.
    CFN92016 8-Prenylnaringenin

    1. 8-Prenylnaringenin is a phytoestrogen with the highest estrogenic activity.
    2. 8-Prenylnaringenin and 6-prenylnaringenin shows slight activity in this assay but significant activity by immunostaining.
    3. 8-Prenylnaringenin at all assayed doses (0.001-20 µM) presumably improves mitochondrial function, whereas a high dose of XN (5 µM) worsens the functionality of this organelle.
    4. 8-Prenylnaringenin has more potent effects on promoting osteoblastic bone formation and inhibiting osteoclastic bone resorption by ERα instead of ERβ than the two classic phytoestrogens: genistein and daidzein.
    CFN92299 8-Shogaol

    1. 8-Shogaol can induce apoptosis in a time- and concentration-dependent manner by reactive oxygen species production and depletion of glutathione in HL-60 cells.
    CFN92011 9-Methoxycanthin-6-one

    1. 9-Methoxycanthin-6-one has anti-tumour activity, exhibits cytotoxic activity towards KB, LU-1, LNCaP, HL-60 cancer cells and other human cancer cell lines with IC50 values around 1-4 μg/mL.
    CFN90168 Absinthiin

    1. Absinthiin is a weak HIV-1 protease inhibitor.
    CFN98744 Acacetin

    1. Acacetin has anti-plasmodial activity .
    2. Acacetin has anti-peroxidant activity .
    3. Acacetin is an ATP-competitive PI3-K inhibitor.
    4. Acacetin has anti-cancer and antitumor activities, such as prostate cancer, melanoma angiogenesis tumor , via Akt/NF-κB,Stat signaling pathway.
    5. Acacetin has anti-inflammatory and antiarthritic effects in FLSs, can inhibit p38 and JNK phosphorylation and reduces MMP-1, MMP-3 and MMP-13 expression in interleukin-1β-induced FLSs.
    CFN97220 Acanthoside B

    1.Acanthoside has inhibitory effects on the allergic inflammation.
    CFN90523 Acetyl shikonin

    1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC50 of over 20 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and angiogenic factors.
    2. Acetylshikonin inhibits the generation of NADPH oxidase complex in the activation of respiratory burst of PMNs, but does not directly inhibit the activity of NADPH oxidase already generated.
    3. Certain shikonin derivatives(such as Acetyl shikonin) act as modulators of the Nur77-mediated apoptotic pathway and identify a new shikonin-based lead that targets Nur77 for apoptosis induction.
    4. Acetylshikonin, shikonin, and alkannin have accelerative effect on the proliferation of granulation tissue in rats.
    5. Acetylshikonin has inhibitory effect on the edematous response is due neither to the release of steroid hormones from the adrenal gland nor to the glucocorticoid activity, but probably partly to the suppression of mast cell degranulation and partly to protection of the vasculature from mediator challenge.
    6. Acetylshikonin induces apoptosis of hepatitis B virus X protein-expressing human hepatocellular carcinoma cells via endoplasmic reticulum stress.
    CFN90308 Acetylshikonin

    1. Acetylshikonin (ASK), a derivate of shikonin, can effectively inhibit tumor cells.
    2. Acetylshikonin can be used to treat hepatocellular carcinoma cells expressing hepatitis B virus X protein (HBX) by inducing ER stress , an oncoprotein from hepatitis B virus.
    3. Acetylshikonin exhibits the most potent antiapoptosis activity through the inhibition of the generation of reactive oxygen species as well as protection of the loss of mitochondria membrane potential.
    4. Acetylshikonin inhibits the production of eicosanoid, is due to the attenuation of cytosolic phospholipase A(2) membrane recruitment via the decrease in [Ca(2+)](i) and to the blockade of cyclooxygenase and 5-lipoxygenase activity.