Science | Nature | Cell | View More
Screening Libraries
Anti-Atherosclerotic Compound Library
A unique collection of 64 Anti-Atherosclerotic Compound Library for high throughput screening (HTS), high content screening (HCS) and New drug research
Cat. Size Price Stock
L200211mg/well * 64 CompoundsInquiry In stock
Contact Us
L20021100uL/well (10mM solution) * 64 CompoundsInquiry In stock
*You can select compounds, quantities, format (dry/solid or DMSO) and plate map to meet your specific requirement.
Contact Us
E-mail manager@chemfaces.com
Tel (0086)-27-8423-7683
Shelf Life (0086)-27-84254680
ManufacturerWuhan ChemFaces Biochemical Co., Ltd.
Package & Storage
Container 96 Well Format Sample
Storage Protected from air and light, refrigerate or freeze(2-8 °)
Shelf Life 24 months (2-8 °)
Intended UseFor research use only. Not for human use. Not sell to patients
Description & Advantages
1. The products in the ChemFaces screening libraries are all from plants.
2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research.
3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools.
4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity.
5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution).
Natural Products
Catalog No. Information
CFN99024 Piceatannol

Piceatannol has antitumor, antioxidant, and anti-inflammatory activities, it also has the potential to control obesity. Piceatannol inhibits effector T cell functions by suppressing TcR signaling.
CFN99106 Glycitein

Gycitein has antioxidant, weak estrogenic, anti-invasion, and anti-proliferation activities, it has potentiol to prevent Abeta associated neurodegenerative disorders, and atherosclerotic cardiovascular diseases. It is a potent activator of ERK1/2, decreases RWPE-1 cell proliferation, it induces ERK1/2 activation was dependent, in part, on tyrosine kinase activity associated with vascular endothelial growth factor receptor (VEGFR).
CFN99434 Tormentic acid

Tormentic acid has anticancer, anti-inflammatory, anti-atherogenic , anti-allodynic, and hepatoprotective properties, it can inhibit markedly the neuropathic allodynia induced by partial ligation of the sciatic nerve. Tormentic acid potently inhibits the production of nitric oxide (NO) in RAW 264.7 cells, also suppresses the LPS-stimulated degradation and phosphorylation of inhibitor of kappa B-α (IκB-α), suggests that the anti-inflammatory activity of TA is associated with the down-regulation of iNOS, COX-2, and TNF-α through the negative regulation of the NF-κB pathway in RAW 264.7 cells.
CFN99458 Ergosterol peroxide glucoside

Ergosterol peroxide exhibits anti-cancer, amoebicidal, anticomplementary, antibacterial, antiviral, anti-oxdiant, and anti-melanogenic activities. Ergosterol peroxide could as an anti-atherosclerosis agent, it exhibits hACAT-1 and Lp-PLA2 inhibitory effects, with inhibitory values of 51.6 +/- 0.9 and 51.7 +/- 1.2%, at a treatment concentration of 0.23 mM. Ergosterol peroxide has osteoclastogenesis inhibitory effect, it shows an inhibitory effect in a dose-dependent manner and an inhibition rate of up to 62% with low cytotoxicity, even at a concentration as low as 1.0 microg/mL.
CFN99539 Danshensu

Danshensu has anxiolytic-like, cardioprotective, neuroprotective, and antioxidant activities. It can enhance HO-1 expression to suppress 6-OHDA-induced oxidative damage via PI3K/Akt/Nrf2 signaling pathways and can reduce 6-OHDA-induced dopaminergic neuronal loss in zebrafish. Chronic treatment with danshensu can prevent/attenuate the formation of atherosclerosis.
CFN99555 Naringin

Naringin exhibits antioxidant, anti-atherogenic, antiulcer, anti-hypocholesterolemic, anti-lipoperoxidative, and anti-hyperglycemia effects. Naringin reduces Ara-C-induced oxidative stress through both an inhibition of the generation of ROS production and an increase in antioxidant enzyme activities, it blocks apoptosis caused by Ara-C-induced oxidative stress, resulting in the inhibition of the cytotoxicity of Ara-C. Naringin attenuates epidermal growth factor (EGF)-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways.
CFN99595 Senkyunolide H

Senkyunolide H in cnidium rhizome may be a prototype for an anti-atherosclerotic drug, it can reduce the metamorphose damage of the RBC caused by ConA, the aggregation of the RBC also could be alleviated by it.
CFN99731 Glabridin

Glabridin is a GABAA receptor positive modulator promoting fatty acid oxidation and improving learning and memory, which has antioxidative,anti-inflammatory, antimalarial, estrogen receptor agonism, anti-metastasis, anti-melanogenesis and neuroprotective effects. Glabridin may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells.
CFN99760 Diosgenin glucoside

Diosgenin glucoside and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis.
CFN99918 Dihydrocapsaicin

Dihydrocapsaicin, a potential inducer of autophagy, has cytotoxic activity. It has anti-atherogenic activity, can reduce the susceptibility of low-density lipoprotein (LDL) to oxidation. Dihydrocapsaicin treatment depletes peptidergic nerve fibers of substance P and alters mast cell density in the respiratory tract of neonatal sheep.