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12-Demethylneocaesalpin F
12-Demethylneocaesalpin F
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 12-Demethylneocaesalpin F
Price:
CAS No.: 1228964-10-0
Catalog No.: CFN96319
Molecular Formula: C27H34O7
Molecular Weight: 470.6 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Caesalpinia pulcherrima
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Description: Reference standards.
12-Demethylneocaesalpin F Description
Source: The herbs of Caesalpinia pulcherrima
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1249 mL 10.6247 mL 21.2495 mL 42.4989 mL 53.1237 mL
5 mM 0.425 mL 2.1249 mL 4.2499 mL 8.4998 mL 10.6247 mL
10 mM 0.2125 mL 1.0625 mL 2.1249 mL 4.2499 mL 5.3124 mL
50 mM 0.0425 mL 0.2125 mL 0.425 mL 0.85 mL 1.0625 mL
100 mM 0.0212 mL 0.1062 mL 0.2125 mL 0.425 mL 0.5312 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Bioorganic & Medicinal Chemistry Letters, 2010, 20(9):2847-2850.
Ulster Journal of Archaeology.[Reference: WebLink]

METHODS AND RESULTS:
Chemical investigation on Caesalpinia crista afforded two new diterpenoids, 6β-cinnamoyloxy-7β-acetoxyvouacapen-5α-ol and 6β,7β-dibenzoyloxyvouacapen-5α-ol and on Caesalpinia pulcherrima another new diterpenoid, 12-Demethylneocaesalpin F along with several known constituents. The structures of the new compounds were settled from their 1D and 2D NMR spectral data.
CONCLUSIONS:
The cytotoxicity of these compounds was measured on two different cancer cell lines.
CFN96258Isovouacapenol C455255-15-9438.6C27H34O5
CFN91966Ajuforrestin A157110-18-4324.37C20H20O4
CFN96963Neocaesalpin O1053189-53-9506.54C26H34O10
CFN89372Neocaesalpin L952473-86-8524.55C26H36O11
CFN9631912-Demethylneocaesalpin F1228964-10-0470.6C27H34O7
CFN890317-O-Acetylneocaesalpin N1309079-08-0494.53C25H34O10
CFN89378Minaxin C1418150-06-7542.57C26H38O12
CFN89082Caesalpine A1616757-59-5420.50C23H32O7
CFN89083Caesalpine B1616757-60-8418.48C23H30O7
CFN89369Bonducellpin C197781-84-3420.49C23H32O7
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