1. Yohimbine is an alkaloid with stimulant and aphrodisiac effects, helping with erections, particularly in those whose erectile dysfunction is due to psychological causes.
2. Yohimbine hydrochloride is an antagonist to xylazine hydrochloride-ketamine hydrochloride immobilization of white-tailed deer.
3. Yohimbine hydrochloride can block alpha 2-adrenergic and dopamine receptors and stimulate serotonergic receptors, it may possible be an antagonist for fescue toxicosis.
4. Yohimbine hydrochloride, a noradrenaline agonist, can facilitate fear extinction, it is thought that the mechanism of enhanced emotional memory is stimulated through elevated noradrenaline levels.
1. Hordenine is an active compound from germinated barley, has a positive inotropic effect upon the heart, increases systolic and diastolic blood pressure, peripheral blood flow volume, inhibits gut movements but has no effect upon the psychomotorical behaviour of mice.
2. Hordenine inhibites melanogenesis by suppressing cAMP production.
1. Silodosin, a selective α-1a receptor antagonist, can increase passage of distal ureteral stones.
2. Silodosin can temporarily improve lower urinary tract symptoms (LUTS), but do not improve the bladder outlet obstruction index (BOOI) after implantation in the prostate, it is a useful option for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia .
3. Silodosin appears to suppress ejaculation in a relatively higher percent of trial participants, this suppression of ejaculation by silodosin suggested its potential for treating premature ejaculation.
1. 14-Deoxy-11,12-didehydroandrographolide may cause autophagic morphology in the cells.
2. 14-Deoxy-11,12-didehydroandrographolide shows more potent cytotoxicity against human promonocytic leukemia (THP-1) cells than adherent cancer cell lines.
3. 14-Deoxy-11,12-didehydroandrographolide retains the anti-inflammatory activities of 2 for asthma probably through the inhibition of NF-κB; ameliorates astrocytic pro-inflammatory reactions and prevented PC12 cell death with different efficacies.
1.3-Epi-alpha-yohimbine(Isorauhimbine) has alpha adrenoceptor blocking activities, has cardiovascular effects.