1. Taxifolin inhibits the cellular melanogenesis as effectively as arbutin.
2. Taxifolin inhibits the ovarian cancer cell growth in a dose-dependent manner.
3. Taxifolin inhibits cholesterol synthesis in a dose- and time-dependent manner.
4. Taxifolin is an important natural antioxidant in Russia, used in both the medical and food industries.
1. Loganin reduced the levels of malondialdehyde and increased the levels of superoxide dismutase in serum and kidney.
2. Loganin reduced AGE levels in serum and kidney and downregulated mRNA and protein expression of receptors for AGEs in kidney in diabetic mice.
3. Loganin attenuated neuroinflammatory responses through the inactivation of NF-κB by NF-κB dependent inflammatory pathways and phosphorylation of MAPK in Aβ25-35-induced PC12 cells.
4. Loganin and 7-O-galloyl-D-sedoheptulose have great promise for the treatment of diabetic complications through inhibition of AR.
1. (-)-Huperzine A is a naturally occurring potent reversible AChE inhibitor that penetrates the blood-brain barrier.
2. (-)-Huperzine A can be used as a protectIve agent against lethal dose nerve agent toxicity in guinea pigs.
3. A combination of (+) and (-)-Huperzine A offers better protection than (+)-Hup A.
1. Stigmasterol inhibits cholesterol biosynthesis via inhibition of sterol Delta(24)-reductase in human Caco-2 and HL-60 cell lines.
2. Stigmasterol has indicated that stigmasterol may be useful in prevention of certain cancers, including ovarian, prostate, breast, and colon cancers.
3. Stigmasterol is used as a precursor in the manufacture of synthetic progesterone, a valuable human hormone that plays an important physiological role in the regulatory and tissue rebuilding mechanisms related to estrogen effects, as well as acting as an intermediate in the biosynthesis of androgens, estrogens, and corticoids.
1. (+)-Catechin hydrate has antioxidant activity and is effective in reducing oxidative stress.