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  • Bioactive Products
    Catalog No. Information
    CFN99074 Taraxasterol

    1. Taraxasterol has anti-inflammatory activity.
    2. Taraxasterol inhibits NO, PGE(2), TNF-α, IL-1β and IL-6 production in LPS-induced RAW 264.7 macrophages in a dose-dependent manner.
    CFN99543 Narirutin

    1. Narirutin has antiproliferative property.
    2. Narirutin has anti-oxidant property.
    3. Narirutin has anti-allergic and anti-inflammatory properties , can reduce airway inflammation in ovalbumin (OVA)-sensitized / challenged NC / Nga mice ,a model of allergic eosinophilic airway inflammation.
    CFN99575 Licochalcone A

    1. Licochalcone A exhibits potent antimalarial activity via and might be developed into a new antimalarial drug.
    2. Licochalcone A had anti-tumor activity in all cell lines tested and enhanced the effect of paclitaxel and vinblastine chemotherapy.
    3.Licochalcone A induced apoptosis in MCF-7 and HL-60 cell lines, as demonstrated by cleavage of PARP, the substrate of ICE-like proteases.
    4. Licochalcone A exhibits a strong antileishmanial activity ,that appropriate substituted chalcones might be a new class of antileishmanial drugs.
    CFN99616 3-O-Methylquercetin

    1. 3-O-Methylquercetin may exert its anti-inflammatory effect through the inhibition of iNOS DNA transcription.
    2. 3-O-Methylquercetin is a selective and competitive PDE3/PDE4 inhibitor, and inhibits PDE3 than PDE4 with a low K(m) value.
    3. 3-O-Methylquercetin inhibits total cAMP- and cGMP-phosphodiesterase (PDE) of guinea pig trachealis at low concentrations.
    4. 3-O-Methylquercetin has both anti-inflammatory and bronchodilating effects, and has the potential for use in the treatment of asthma at a dose without affecting blood pressure.
    CFN98006 Bavachinin

    1. Bavachinin could be used as a therapeutic agent for inhibiting tumor angiogenesis.
    2. Bavachinin can inhibit tube formation in human umbilical vein endothelial cells (HUVECs) as well as in vitro migration of KB cells.
    3. Bavachinin decreases transcription of genes associated with angiogenesis and energy metabolism that are regulated by HIF-1, such as vascular endothelial growth factors (VEGF), Glut 1 and Hexokinase.
    4. Bavachinin inhibits increases in HIF-1α activity in human KB carcinoma (HeLa cell derivative) and human HOS osteosarcoma cells under hypoxia in a concentration-dependent manner, probably by enhancing the interaction between von Hippel-Lindau (VHL) and HIF-1α.