Bioactive Products
| A unique collection of 184 natural compounds used for Antibacterial research. | ||
| Catalog No: | Bb192 | Antibacterial Compound Library Screening Details |
| Size: | 1mg/well * 184 Compounds 2mg/well * 184 Compounds | |
| Cat. No. | Information |
| CFN98531 | Miltirone Miltirone is a CYPs inhibition, it has been characterized as a low-affinity ligand for central benzodiazepine receptors, it might ameliorate the symptoms associated with discontinuation of long-term administration of ethanol or of other positive modulators of the GABA A receptor. Miltirone possesses significant anticancer, antibacterial, antioxidant, and anti-inflammatory activities, the hepatocyte metabolism is the major route of clearance for miltirone. Miltirone is collateral sensitive in multidrug-resistant P-gp-overexpressing cells, induces G2/M arrest, and triggeres apoptosis via ROS-generated breakdown of MMP and DNA damage. Miltirone has antiprotozoal activity against T. brucei rhodesiense STIB 900. |
| CFN98538 | Isocolumbin Isocolumbin has anti-inflammatory, and antimicrobial activities. |
| CFN98540 | Oroxylin A Oroxylin A has anticancer,.anti-inflammation, antithrombotic,antibacterial, anti-pruritic effects, it can inhibit LPS-induced iNOS and COX-2 gene expression by blocking NF-κB activation. Oroxylin A reverses MDR by G2/M arrest and the underlying mechanism attributed to the suppression of P-gp expression via Chk2/P53/NF-κB signaling pathway. Oroxylin A facilitates memory consolidation through brain-derived neurotrophic factor (BDNF)-TrkB signaling. |
| CFN98495 | 6-Hydroxystigmasta-4,22-dien-3-one 6β-Hydroxystigmasta-4,22-dien-3-one exhibits in vitro antibacterial activity; it also shows antioxidant activity, the value of IC50 toward DPPH is 233.4 ± 0.28 uM. |
| CFN98548 | Pseudolycorine Pseudolycorine, primarily studied as a new antiviral agent , it also shows remarkable antileukemic activity; it can halt HeLa cell growth at 10-1 mM or lower concentrations, it at its growth inhibitory concentrations blocks protein synthesis in ascites cells and stabilize HeLa cell polysomes in vivo. Pseudolycorine and haemanthamine show good activity in in vitro assays against Trypanosoma brucei rhodesiense, T. cruzi and Plasmodium falciparum with IC50 values in the range of 3.66 uM or lower. |
