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  • Bioactive Products
    Antileukaemic Compound Library
    A unique collection of 35 Antileukaemic natural compound library for Antileukaemic screening
    Catalog No: B29 Antileukaemic Compound Library
    Screening Details
    Size: 1mg/well * 35 Compounds
    2mg/well * 35 Compounds
    Catalog No. Information
    CFN99024 Piceatannol

    1. Piceatannol has antitumor activity.
    2. Piceatannol has the potential to control obesity.
    3. Piceatannol has antioxidant, and anti-inflammatory activities.
    4. Piceatannol inhibits effector T cell functions by suppressing TcR signaling.
    CFN99085 Ganodermanondiol

    1. Ganodermanondiol shows a strong anticomplement activity.
    2. Ganodermanondiol against tert-butyl hydroperoxide-induced hepatotoxicity through Nrf2-mediated antioxidant enzymes.
    CFN99491 Hispidulin

    1. Hispidulin has antineoplastic activity.
    2. Hispidulin has antioxidant properties and effect on mitochondrial energy metabolism.
    3. Hispidulin has a potential treatment for hyper-dopaminergic disorders.
    4. Hispidulin has considerable antiepileptic, neuroprotective, and antiinflammatory effects on kainic acid-induced seizures in rats.
    5. Hispidulin exerts anti-osteoporotic and bone resorption attenuating effects via activating the AMPK signaling pathway.
    CFN99563 Coptisine

    1. Coptisine treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2,3-dioxygenase .
    2. Coptisine treats myocardial I/R likely through suppressing myocardial apoptosis and inflammation by inhibiting the Rho/ROCK pathway.
    3. Coptisine is a potential anti-osteosarcoma drug candidate,via exerting a strong anti-osteosarcoma effect with very low toxicity .
    4. Coptisine with a high dosage could inhibit cholesterol synthesis via suppressing the HMGCR expression and promoting the use and excretion of cholesterol via up-regulating LDLR and CYP7A1 expression.
    5. Coptisine suppresses adhesion, migration and invasion of MDA-MB-231 breast cancer cells in vitro, the down-regulation of MMP-9 in combination with the increase of TIMP-1 possibly contributing to the anti-metastatic function for breast cancer.
    CFN99710 Wogonoside

    1. Wogonoside has anti-inflammatory effect, via dual inhibition of NF-κB and NLRP3 inflammasome.
    2. Wogonoside led to reduced Bcl-2 expression and increased Bax expression, while as it led to s decrease in the levels of mitochondrial cytochrome c and an increase in cytosolic fraction and expressions of cytosolic apoptotic protease activating factor-1 (Apaf-1).
    3. Wogonoside has shown preclinical anticancer efficacy in various cancer models.