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  • Bioactive Products
    Catalog No. Information
    CFN99621 Marmin

    1. Marmin and nobiletin are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the prevention of the effects of endogenous acetylcholine and histamine.
    2. Marmin could inhibit contraction of the guinea-pig tracheal smooth muscle, especially by interfering histamine receptor, inhibiting the histamine release from mast, inhibiting intracellular Ca(2+) release from the intracellular store and the Ca(2+) influx through voltage-dependent Ca(2+) channels.
    CFN98047 Gentiopicroside

    1. The function of Gentiopicroside on acute pancreatitis may be related to inhibiting the release of inflammatory mediators and NF-κB p65 protein expression.
    2. The mechanisms of Gentiopicroside' prokinetic effect were associated with modulating the levels of SST and GAS in plasma, raising the expressions of MTLR in gastric antrum, duodenum, ileum and jejunum, reducing the expression of VIPR2 in duodenum and activating M-R.
    CFN98204 Cytochalasin D

    1. Cytochalasin D-induced extension of neurite-like processes might correlate with enhanced accumulation of PrPres.
    2. Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation.
    3. Cytochalasin D inhibits CT26 tumor growth potentially through inhibition of cell proliferation, induction of cell apoptosis and suppression of tumor angiogenesis.
    4. Cytochalasin D stimulates the expression of TF in B16 melanoma cells, activating both coagulation-dependent and -independent pathways via binding to FVIIa, eventually promoting lung metastasis.
    CFN98254 Allocryptopine

    1. Allocryptopine may be considered safe in terms of possible induction of CYP1A enzymes.
    2. Both Allocryptopine and BTHP derived from Chinese herbs potently block hERG current.
    3. Allocryptopine induces a relaxing effect on the ileum by inhibiting phosphodiesterase enzyme, and thus elevating cellular cAMP and its contractile effect on the urinary bladder by affecting alpha-adrenergic receptors in this tissue.
    CFN98158 Scopolamine butylbromide

    1. Scopolamine butylbromide is an anti-secretive drug.
    2. Scopolamine butylbromide has a potential anti-tumor activity.
    3. Scopolamine butylbromide possesses anticholinergic effects.
    4. Scopolamine butylbromide is a non-subtype-selective muscarinic receptor antagonist.
    5. Scopolamine butylbromide (0.2 mg.kg-1) was effective in preventing succinylcholine-induced bradycardia in infants and children.