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  • Bioactive Products
    Catalog No. Information
    CFN98737 Orobol

    1. Orobol has sensitization effect may be by mitochondrial alterations in these cells .
    2. Orobol produces cisplatin sensitivity in human ovarian carcinoma cells by inducing apoptosis through the MT-dependent signaling pathway.
    3. Orobol and platelet derived growth factor regulate PX sensitivity by reciprocally altering the proportion of tubulin isotype expression and PX-induced apoptotic signaling.
    CFN90421 4-Methylumbelliferone

    1. 4-Methylumbelliferone can treat biliary spasm.
    2. 4-Methylumbelliferone has anti-cancer activity, the mechanism based on its antioxidation in organisms.
    3. 4-Methylumbelliferone may inhibit the phosphorylation of HAS2 by PKC through the stimulation of O-GlcNAcylation.
    4. 4-Methylumbelliferone similarly ameliorate hypertriglyceridemia and hyperglycemia partly by modulating hepatic lipid metabolism and the antioxidant defense system along with increasing adiponectin levels.
    CFN92073 Kuguacin J

    1. Kuguacin J exerts growth inhibition through G1 arrest and induction of apoptosis in androgen-dependent human prostate cancer, it is a promising candidate new antineoplastic and chemopreventive agent for androgen-dependent prostate cancer and carcinogenesis.
    2. Kuguacin J modulates the function of P-glycoprotein (P-gp) by directly interacting at the drug-substrate-binding site, and it appears to be an effective inhibitor of P-gp activity in vitro and thus could be developed as an effective chemosensitizer to treat multidrug-resistant cancers.