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  • Bioactive Products
    Catalog No. Information
    CFN99106 Glycitein

    1. Gycitein has weak estrogenic activity.
    2. Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.
    CFN99722 Secoisolariciresinol Diglucoside

    1. Secoisolariciresinol Diglucoside was cytoprotective in an in vitro model of iron overload induced redox-inflammatory damage.
    2. Synthetic Secoisolariciresinol Diglucoside at 25 mg/kg b.w., exerts anti hyperglycemic effect by preventing the liver from peroxidation damage through inhibition of ROS level mediated increased level of enzymatic and non-enzymatic antioxidants.
    3. Secoisolariciresinol Diglucoside has renoprotective effects in HFD/STZ-induced DN in rats through correction of hyperglycemia.
    (1) Attenuation of oxidative/nitrosative stress markers;
    (2) Downregulation of renal expressions of inflammatory markers NF-κB, TNF-α, and iNOS;
    (3) Along with upregulation of renal expressions of antiapoptotic markers survivin and Bcl-2;
    (4) Maintain tissue function which results in improving the sensitivity and response of target cells in STZ-induced diabetic rats to insulin.
    CFN99731 Glabridin

    1. Glabridin may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction,through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells.
    2. Glabridin may have potential as a chemopreventive agent against liver cancer metastasis, by inhibiting the invasion of human HCC cells.
    CFN99921 Tectoridin

    1. Tectoridin possesses a estrogenic and thyroid hormone-like agent by activating estrogen and thyroid hormone receptors.
    2. Tectoridin has anti-oxidant, anti-inflammatory and hypoglycemic activities; Tectoridin and its five metabolites inhibits the activities of lens aldose reductase in rat (IC₅₀: 1.4-15.5 μM).
    CFN98431 Hypophyllanthin

    1. Hypophyllanthin can directly inhibit P-gp activity and did not interfere with MRP2 activity, it may reversibly inhibit P-gp function.
    2. Hypophyllanthin can modulate the vascular tension via the endothelium-independent mechanisms.