|A unique collection of 165 natural compounds used for Hepatoprotective research and Hepatoprotective drug screening.|
|Catalog No:||B36|| Hepatoprotective Compound Library
|Size:||1mg/well * 165 Compounds|
2mg/well * 165 Compounds
D-Pinitol is a safe nutrient to reduce calorie consumption when supplementing with creatine. It exerts anti-inflammatory, insulin-like activities; and inhibits osteoclastogenesis from bone marrow stromal cells and macrophage cells, which in turn protect bone loss from ovariectomy. It inhibits the activation of p38, JNK, and NF-κB, the expression of p53, Bcl-2, Bax and NF-kB proteins, and reduces focal adhesion kinase (FAK) phosphorylation, c-Src kinase activity.
Bakuchiol possesses anti-tumor, cytotoxic, anti-bacterial , and anti-helmenthic properties, it shows DNA polymerase1 inhibiting activity. Bakuchiol has great potential for use in food additives and mouthwash for preventing and treating dental caries.
1. Phyllanthin is widely used as hepatoprotective and antigenotoxic and inhibit function of P-gp.
1. Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2.
2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transplantation.
Ganodermanontriol has anti-cancer, hepatoprotective, anti-inflammatory, and antioxidative activities, it also shows a strong anticomplement activity against the classical pathway (CP) of the complement system with IC(50) values of 17.2 microM. Ganodermanontriol is active as an anti-HIV-1 agent with an inhibitory concentration of 7.8 micrograms ml-1.It has a wide spectrum of targets including HO-1, PI3K/Akt and p38 kinases.