|CFN99505||Aristolochic acid A
1. Aristolochic acid A has anticancer activity.
2. Aristolochic acid A has high inhibition of thrombin activity.
3. Aristolochic acid A is a nature calcium antagonist.
4. Aristolochic acid A is a potent nephrotoxin.
5. Aristolochic acid A strongly induces toxic damage during ovarian maturation by inhibiting Akt phosphorylation-mediated suppression of apoptosis.
1. Colchicine has anti-cancer activity.
2. Colchicine is a anti-gout agent.
3. Colchicine is used to treat familial Mediterranean fever.
4. Colchicine is used as an anti-inflammatory agent for long-term treatment of Behçet's disease.
5. Colchicine inhibits microtubule polymerization by binding to tubulin, one of the main constituents of microtubules.
6. Colchicine is also used for constipation-predominant irritable bowel syndrome in women, and for treatment of severe or persistent aphthous stomatitis (canker sores).
1. Telocinobufagin is the major endogenous digitalis-like factor.
2. Telocinobufagin significantly decreases the bacterial burdens in the spleen and prolongs the survival time of FIST-immunized mice challenged with live S. typhimurium.
3. Telocinobufagin has immunomodulatory activity, can enhance a Th1 immune response to control intracellular infections, could be developed as a novel immunotherapeutic agent to treat cancer and other immune-mediated diseases.
1. Gardenoside has laxative, cholagogic activities.
2. Gardenoside has anti-inflammatory, analgesic activities.
3. Gardenoside can treat soft tissue damage .
4. Gardenoside can inhibit the secretion of gastric juice and reduce the role of pancreatic amylase.