Bioactive Products
| A unique collection of 223 Neuroprotection natural compounds for high throughput screening (HTS) | ||
| Catalog No: | B72a21 | Neuroprotection Compound Library Screening Details |
| Size: | 1mg/well * 223 Compounds 2mg/well * 223 Compounds | |
| Cat. No. | Information |
| CFN99948 | Bilirubin Bilirubin is a tetrapyrrole and a breakdown product of heme catabolism, it is a prominent endogenous antioxidant cytoprotectant and a natural inhibitor of vascular smooth muscle cell proliferation, which has neuroprotective and anti- atherosclerosis-related diseases effects. It can act as an effective agent to reduce mortality and counteract hypotension elicited by endotoxin through mechanisms involving a decreased NOS2 induction secondary to inhibition of NAD(P)H oxidase. |
| CFN99950 | Hydroxysafflor yellow A Hydroxysafflor yellow A(H-A) possesses hepatoprotective, anti-inflammatory, and anti-tumor activities, it can effectively protect the liver of rats from long-term alcohol injury, which relates with the enhanced antioxidant capacity of liver tissues and inhibition of TGF-β1 expression, it also inhibited angiogenesis of hepatocellular carcinoma via blocking ERK/MAPK and NF-κB signaling pathway in H22 tumor-bearing mice. H-A also can provide protection to H9c2 cardiomyocytes against A/R-induced apoptosis by the upregulation of HO-1 expression through the PI3K/Akt/Nrf2 signaling pathway. |
| CFN98012 | Methyllucidone Methyllucidone may have a neuroprotective potential via inhibition of neurotoxic microglial activation implicated in neurodegeneration.It can strongly inhibit the growth of human cancer cells and colon tumor xenografted in nude mice, the anti-tumor effects are further confirmed with caspase-3 activation and degradation of PARP. Methyllucidone shows 85% antifungal activity at 50 against the disease wheat leaf rust. |
| CFN98026 | Tiliroside Tiliroside possesses anti-inflammatory, antioxidant, anti-complement, anti-diabetic, anticarcinogenic and hepatoprotective activities. Tiliroside enhances fatty acid oxidation via the enhancement adiponectin signaling associated with the activation of both AMP-activated protein kinase and peroxisome proliferator-activated receptor α and ameliorates obesity-induced metabolic disorders. |
| CFN99958 | (-)-Huperzine A (-)-Huperzine A is a naturally occurring potent reversible AChE inhibitor that penetrates the blood-brain barrier, it also has several neuroprotective effects including modification of beta-amyloid peptide, reduction of oxidative stress, anti-inflammatory, anti-apoptotic and induction and regulation of nerve growth factor. |
