Xylitol, a commonly used sweetener, it can inhibit the growth of pneumococci, it is effective in preventing otitis media and decreasing the need for antimicrobials when xylitol sugar given in a syrup or chewing gum. Xylitol is also a widely used anti-caries agent that has anti-inflammatory and anti-cancer effects, it inhibits salivary lysozyme activity.
Guaijaverin is a urease inhibitor, it (IC(50)=0.18 microM) shows an inhibitory effect on rat lens aldose reductase. Guaijaverin has antioxidant, hypoglycemic activity and inhibitory capacity against free fatty acid release.It demonstrates high potential antiplaque agent by inhibiting the growth of the Strep. Mutans.
Sanguinarine possesses anticancer, antimicrobial, anti-inflammatory, and antioxidant properties, it has therapeutic potential in preventing the neurodegenerative diseases, it may be used to develop a potential therapeutic drug for treating cardiac remodeling and heart failure and shows protective effects on teeth and alveolar bone health. Sanguinarine can inhibit osteoclast formation and bone resorption via suppressing RANKL-induced activation of NF-κB and ERK signaling pathways, and can protect against cardiac hypertrophy and fibrosis via inhibiting NF-κB activation.
α-Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
6,8-Diprenylgenistein has antimicrobial activity, it has anti-bacteria activity against Gram-negative and Gram-positive bacteria.