Natural Products
Desmethylxanthohumol
| Catalog No. | CFN92015 |  |
| CAS No. | 115063-39-3 | |
| Molecular Weight: | 340.4 | |
| Molecular Formula | C20H20O5 | |
| DBs | [PubChem]:274954377 [ChEMBL]:80489 [PCIDB]: |
Standard InChI:
InChI=1S/C20H20O5/c1-12(2)3-9-15-17(23)11-18(24)19(20(15)25)16(22)10-6-13-4-7-14(21)8-5-13/h3-8,10-11,21,23-25H,9H2,1-2H3/b10-6+
Biological Activity
Desmethylxanthohumol is a chalcone-type compound isolated from hops, it is present in extracts in a concentration of about 1/5 of the xanthohumol content.; it is a phytoestrogen with hormonal activity; it is a powerful apoptosis inducing agent in lymphoid leukemic cell assays and it acts as a chemoprotective compound activating oxidation and excretion of harmful xenobiotic.[1]
Desmethylxanthohumol has oxygen radical antioxidant capacity.[2]
Desmethylxanthohumol is prenylated flavonoid from hops effectively, can inhibit proliferation of prostate cancer cells in vitro.[3]
Product
Official website: Desmethylxanthohumol
Japanese website: Desmethylxanthohumol
Chinese website: Desmethylxanthohumol
Japanese website: Desmethylxanthohumol
Chinese website: Desmethylxanthohumol
References
[1] Reinhard A. Diller, Herbert M. Riepl, Oliver Rose,et al. Beer in Health and Disease Prevention,2008,9.
[2] Vogel S, Ohmayer S, Brunner G, et al. Bioorg Med Chem, 2008, 16(8):4286-93.
[3] Delmulle L, Bellahcène A, Dhooge W, et al. Phytomedicine, 2006, 13(9-10):732-4.
[4] Zhu LJ, Liu B, Shi R B. Journal of Pharmaceutical Analysis, 2008 (1): 32-5.
Product Use Citation
