Natural Products
Ganoderic acid C2
| Catalog No. | CFN92054 |  |
| CAS No. | 103773-62-2 | |
| Molecular Weight: | 518.7 | |
| Molecular Formula | C30H46O7 | |
| DBs | [PubChem]:274954338 [ChEMBL]: [PCIDB]: |
Standard InChI:
InChI=1S/C30H46O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h15-16,18-19,21-23,32,34-35H,8-14H2,1-7H3,(H,36,37)/t15-,16-,18-,19+,21?,22+,23+,28+,29-,30+/m1/s1
Biological Activity
Ganoderic acid C2, isolated from the spores, has cytotoxicity in vitro against Meth-A and LLC cell lines.[1]
CHCl(3) extract of the fruiting body of Ganoderma lucidum was found to show inhibitory activity on human aldose reductase in vitro, and ganoderic acid C2 and ganoderenic acid A is essential in eliciting the inhibitory activity considering the much lower activity of their methyl esters.[2]
Ganoderenic acid C2 exhibits hepatoprotective activities against DL-galactosamine-induced cell damage in HL-7702 cells. [3]
Product
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Japanese website: Ganoderic acid C2
Chinese website: Ganoderic acid C2
References
[1] Min B S, Gao J J, Nakamura N, et al. Cheminform, 2000, 31(50):1026-33.
[2] Fatmawati S, Shimizu K, Kondo R.Planta Med, 2010, 76(15):1691-3.
[3] Liu L Y, Hui C, Chao L, et al. Fitoterapia, 2014, 98:254-9.
[4] Zhao J, Chen X, Kaishun B I. China journal of Chinese materia medica, 2009, 34(17):2220-2.
Product Use Citation
