Natural Products
Isomahanine
| Catalog No. | CFN92200 |  |
| CAS No. | 144606-95-1 | |
| Molecular Weight: | 347.5 | |
| Molecular Formula | C23H25NO2 | |
| DBs | [PubChem]:274954192 [ChEMBL]: [PCIDB]: |
Standard InChI:
InChI=1S/C23H25NO2/c1-14(2)6-5-10-23(4)11-9-17-21(26-23)8-7-16-18-12-15(3)20(25)13-19(18)24-22(16)17/h6-9,11-13,24-25H,5,10H2,1-4H3
Biological Activity
Isomahanine and mahanine , isolated from the ethyl acetate extract of Murraya koenegii (Rutaceae) leaves, show antibacterial activity towards Flavobacterium columnare and Streptococcus iniae which caused columnaris disease and streptococcosis respectively; isomahanine has the strongest activity against F. columnare (isolate ALM-00-173) and S. iniae (isolate LA94-426) based on 24-h 50% inhibition concentration (IC50) and minimum inhibition concentration (MIC). [1]
Isomahanine is a potent inhibitor of sEH , with IC50 values of 22.565±651.7 . [2]
Product
References
[1] Meepagala K M, Schrader K K, Burandt C L. J Agr Chem Env, 2013, 02(4):90-100.
[2] Kim J H, Morgan A M, Tai B H, et al. J Enzym Inhib Med Ch, 2015:1-5.
Product Use Citation
