Natural Products
Cucurbitadienol
| Catalog No. | CFN92378 |  |
| CAS No. | 35012-08-9 | |
| Molecular Weight: | 426.7 | |
| Molecular Formula | C30H50O | |
| DBs | [PubChem]:274954019 [ChEMBL]:62456 [PCIDB]: |
Standard InChI:
InChI=1S/C30H50O/c1-20(2)10-9-11-21(3)22-16-17-30(8)25-14-12-23-24(13-15-26(31)27(23,4)5)28(25,6)18-19-29(22,30)7/h10,12,21-22,24-26,31H,9,11,13-19H2,1-8H3/t21-,22-,24-,25-,26+,28+,29-,30+/m1/s1
Biological Activity
Cucurbitadienol is Cucurbitane type tetracyclic triterpenoids, isolated from a variety of plants in the Cucurbitaceae, has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate.[1]
Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis.[2]
CYP87D18 catalyzed the oxidation of cucurbitadienol at C-11 to produce 11-oxo cucurbitadienol and 11-hydroxy cucurbitadienol.[3]
Product
Official website: Cucurbitadienol
Japanese website: Cucurbitadienol
Chinese website: Cucurbitadienol
Japanese website: Cucurbitadienol
Chinese website: Cucurbitadienol
References
[1] Luo Z L, Zhang K L, Ma X J, et al. Pharm Biotechno, 2016 (2).
[2] Shibuya M, Adachi S, Ebizuka Y. Cheminform, 2004, 35(45):6995-7003.
[3] Zhang J, Dai L, Yang J, et al. Plant & Cell Physiol, 2016,57(5):1000-7.
Product Use Citation
