Artemisinic acid

Catalog No.	CFN97276
CAS No.	80286-58-4
Molecular Weight:	234.3
Molecular Formula	C15H22O2
DBs	[PubChem]:274953108 [ChEMBL]:63749 [PCIDB]:

Standard InChI:

InChI=1S/C15H22O2/c1-9-4-6-12-10(2)5-7-13(14(12)8-9)11(3)15(16)17/h8,10,12-14H,3-7H2,1-2H3,(H,16,17)/t10-,12+,13+,14+/m1/s1

Biological Activity

Artemisinic acid, is the immediate precursor of the semi-synthesis artemisinin, could be a cost-effective, environmentally friendly, high-quality and reliable source of artemisinin;and artemisinin is highly effective against multi-drug-resistant Plasmodium spp. ^[1]

Artemisinic acid was studied as a novel elicitor to enhance the yield of terpenoid indole alkaloids, artemisinic acid can up-regulate the transcriptions of tryptophan decarboxylase, geraniol 10-hydroxylase, tabersonine 16-hydroxylase and deacetoxyvindoline 4-hydroxylase.^[2]

Artemisinic acid is a regulator of adipocyte differentiation and C/EBP δ expression, it can inhibit adipogenic differentiation of hAMSCs by occurs primarily through reduced expression of δ, which is mediated by the inhibition of and suggest that artemisinic acid may be used as a complementary treatment option for associated with metabolic syndrome.^[3]