Natural Products
Lyoniside
| Catalog No. | CFN98451 |  |
| CAS No. | 34425-25-7 | |
| Molecular Weight: | 552.6 | |
| Molecular Formula | C27H36O12 | |
| DBs | [PubChem]:274951370 [ChEMBL]: [PCIDB]: |
Standard InChI:
InChI=1S/C27H36O12/c1-34-17-7-13(8-18(35-2)23(17)31)20-15(10-38-27-25(33)22(30)16(29)11-39-27)14(9-28)5-12-6-19(36-3)24(32)26(37-4)21(12)20/h6-8,14-16,20,22,25,27-33H,5,9-11H2,1-4H3/t14-,15-,16+,20+,22-,25+,27+/m0/s1
Biological Activity
Lyoniside and saracoside are cytotoxic to promastigotes and intracellular amastigotes,
they effectively kill L. donovani amastigotes inside macrophages in vitro , demonstrate strong anti-leishmanial efficacies in BALB/c mice model of leishmaniasis, suggests that these two compounds potential anti-leishmanial candidates. [1]
The synergistic action of lyoniside and triterpene acids was demonstrated in inhibitory effect exerted on germination and growth of Pinus sylvestris .[2]
Product
References
[1] Saha S, Mukherjee T, Chowdhury S, et al. Biochem Pharmacol, 2013, 86(12):1673-87.
[2] Szakiel A, Voutquenne-Nazabadioko L, Henry M. Phytochem Lett, 2011, 4(2):138-43.
[3] Lee B, Jin B W, Yun B R, et al. Pharm Mag, 2014, 10(10):195-9.
Product Use Citation
