Natural Products
10-Gingerol
| Catalog No. | CFN99132 |  |
| CAS No. | 23513-15-7 | |
| Molecular Weight: | 350.49 | |
| Molecular Formula | C21H34O4 | |
| DBs | [PubChem]:274951286 [ChEMBL]: [PCIDB]:31474 |
Standard InChI:
InChI=1S/C21H34O4/c1-3-4-5-6-7-8-9-10-18(22)16-19(23)13-11-17-12-14-20(24)21(15-17)25-2/h12,14-15,18,22,24H,3-11,13,16H2,1-2H3/t18-/m0/s1
Biological Activity
10-Gingerol, fresh ginger extract, inhibits the production of nitric oxide, IL-1β, IL-6 and TNF-α as well as their mRNA levels in LPS-activated BV2 microglia,exhibits a significant anti-neuroinflammatory capacity.[1]
10-Gingerol improves cisplatin-induced anorexia by inhibiting acylated ghrelin degradation.[2]
10-Gingerol inhibits proliferation and invasion of MDA-MB-231 breast cancer cells through suppression of Akt and p38MAPK activity, suggests that it could be a potential therapeutic agent for the prevention and treatment of breast cancer.[3]
10-Gingerol has ameliorative effect on drug induced hepatotoxicity in albino rats.[4]
Product
References
[1] Ho S C, Chang K S, Lin C C. Food Chem, 2013, 141(3):3183-91.
[2] Sadakane C, Muto S, Nakagawa K, et al. Biochem Bioph Res Co, 2011, 412(3):506-11.
[3] Joo J H, Hong S S, Cho Y R, et al. Oncol Rep, 2016, 35(2):779-84.
[4] Saleh I, Alqasoumi. J Med Plants Res, 2012, 6(9): 1548-55.
[5] Lee S, Khoo C, Halstead C W, et al. J Aoac Int, 2007, 90(5):1219-26.
Product Use Citation
