Natural Products
Nicotiflorin
| Catalog No. | CFN99830 |  |
| CAS No. | 17650-84-9 | |
| Molecular Weight: | 594.5 | |
| Molecular Formula | C27H30O15 | |
| DBs | [PubChem]:274951124 [ChEMBL]: [PCIDB]:5169 |
Standard InChI:
InChI=1S/C27H30O15/c1-9-17(31)20(34)22(36)26(39-9)38-8-15-18(32)21(35)23(37)27(41-15)42-25-19(33)16-13(30)6-12(29)7-14(16)40-24(25)10-2-4-11(28)5-3-10/h2-7,9,15,17-18,20-23,26-32,34-37H,8H2,1H3/t9?,15?,17-,18+,20-,21?,22?,23?,26+,27-/m0/s1
Biological Activity
Nicotiflorin is a flavonoid glycoside extracted from a traditional Chinese medicine Flos Carthami, it has a protective effect against cerebral ischemic damage.[1]
Nicotiflorin has protective effects on reducing memory dysfunction, energy metabolism failure and oxidative stress in multi-infarct dementia model rats.[2]
Nicotiflorin has neuroprotection in permanent focal cerebral ischemia and in neuronal cultures. [3]
Product
References
[1] Li R, Guo M, Zhang G, et al. J Ethnopharmacol, 2006, 107(1):143-50.
[2] Huang J, Fu S Y, Cao Y, et al. Pharmacol Biochem Behavior, 2007, 86(4):741-8.
[3] Li R, Guo M, Zhang G, et al. Biol Pharm Bull, 2006, 29(9):1868-72.
[4] Sun J, Xiao-Juan H E, Liu J Q. China Pharmacy, 2015, 9.
Product Use Citation
