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  • Alstonia scholaris

    Alstonia scholaris (Apocynaceae) has been historically used in "dai" ethnopharmacy to treat chronic respiratory diseases. The leaf extract, developed as a commercially available traditional Chinese medicine, used to release tracheitis and cold symptom, has also been prescribed in hospitals and sold over the counter in drug stores.
    Pharmacological evaluation of Alstonia scholaris: anti-inflammatory and analgesic effects. It is decoction of the leaves were used for beriberi. The bark contains the alkaloids ditamine, echitenine and echitamine.
    The alkaloids fraction of Alstonia scholaris leaf, three main alkaloids, picrinine, vallesamine and scholaricine, may produce the anti-inflammatory and analgesic effect peripherally based on several in vivo assays. In in vitro tests, alkaloids exhibited inhibition of inflammatory mediators (COX-1, COX-2 and 5-LOX), which is accordant with results on animal models.

    Alstonia scholaris
    Research products of Alstonia scholaris
    Catalog Product Name CAS Number Manual
    CFN99260N1-Methoxymethyl picrinine1158845-78-3  PDF
    CFN99261Alstonic acid A1159579-44-8  PDF
    CFN99262Alstonic acid B1159579-45-9  PDF
    CFN99377Vallesamine N-oxide126594-73-8  PDF
    CFN98013Picralinal20045-06-1  PDF
    CFN9843219,20-(E)-Vallesamine3368-87-4  PDF
    CFN97014N-Demethylechitamine60048-88-6  n/a
    CFN97168Echitamine6871-44-9  n/a
    CFN974345-Methoxystrictamine870995-64-5  n/a
    CFN97509Leuconolam93710-27-1  n/a